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S24: Creative use of nest generation sequencing techology in evolutionary geomics: solvin old problems with new approaches
Wednesday 11th June, 11th June 15.30 - 17.00
San Geronimo
O-210 Patterns of human mutation rate revealed by sequencing of 250 parent-child trios.
Laurent Francioli1, Paz Polak2, Amnon Koren3, Genome of Netherlands Consortium Genome of Netherlands Consortium4, Paul de Bakker1, Shamil Sunyaev*2
1University of Utrecht Medical Center, The Netherlands, 2Genetics Division, Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, USA, 3Department of Genetics, Harvard Medical School, USA, 4Genome of Netherlands Consortium, The Netherlands
O-211 Quantitative analysis of variation in heterochromatin repeats in Drosophila melanogaster
Kevin Wei, Daniel Barbash, Andrew Clark*
Cornell University, USA
O-212 A new genome-wide method to compare transcriptomes at the isoform-scale.
Mathilde Paris*1, Susan Lott2, Jacqueline Villalta3, Lior Pachter3, Michael Eisen3
1CNRS, France, 2University of California, Davis, USA, 3University of California, Berkeley, USA
O-213 Negative selection facilitates crossing-over in a hypervariable species
Vladimir Seplyarskiy*1,2, Mraria Logacheva1,2, Alex Penin1, Maria Baranova1,2, Eugeny Leushkin1,2, Feodor Kondrashov3, Alex Kondrashov1,4, Tim James4
1Moscow State university, Russia, 2IITP, Russia, 3Bioinformatics and Genomics Programme, Centre for Genomic Regulation, Spain, 4University of Michigan, Ann Arbor, USA