conference logo
Programme  Titles  Presenters 
Manned Poster Session (P-2000- P-2365)

Based on Symposia numbers 15 - 26
P-2230 Quantifying beta diversity over phylogenetic networks
Donovan Parks*, Robert Beiko
Dalhousie University, Canada
P-2261 The Evolution of Cold Tolerance in the Endemic New Zealand Stick Insect Fauna using RNA-Seq: Counts, Pathways and Selection
Luke Thomas Dunning*1,2, Alice Dennis2,3, Richard Newcomb1,4, Thomas Buckley1,2
1Auckland University, New Zealand, 2Landcare Research, New Zealand, 3Allan Wilson Centre for Molecular Ecology and Evolution, New Zealand, 4Plant and Food, New Zealand
P-2005 Comprehensive population genetic modelling unravels the invasion history of four Pristionchus pacificus lineages on La Réunion Island
Angela McGaughran*, Katy Morgan, Ralf Sommer
Max Planck Institute for Developmental Biology, Department for Evoutionary Biology, Germany
P-2318 Accelerated Recruitment of New Brain Development Genes into the Human Genome
Yong Zhang*1,2, Patrick Landback1, Maria Vibranovski1, Manyuan Long1
1Department of Ecology and Evolution, University of Chicago, USA, 2Institute of Zoology, Chinese Academy of Sciences, China
P-2187 The effects of alternative splicing and structural disorderness on exonic evolutionary rates
Feng-Chi Chen*1,2, Chia-Lin Pan1, Hsuan-Yu Lin1
1National Health Research Institutes, Taiwan, 2China Medical University, Taiwan
P-2319 Detection of WGDs by modeling duplication dynamics
Kevin Vanneste*1,2, Yves Van de Peer1,2, Steven Maere1,2
1VIB, Belgium, 2UGent, Belgium
P-2188 A model for the evolution of a uniquely mammalian T cell receptor
Robert Miller*, Zuly Parra
Center for Evolutionary Immunology, University of New Mexico, USA
P-2006 Recent and contrasting evolutionary change in human and chimpanzee bone phenotypes: primate population genetics of type I collagen (COL1A1)
Daryn Stover*2,1, Anne Stone1, Brian Verrelli1
1Arizona State University, USA, 2Simon Fraser University, Canada
P-2001 Evolution of Argonaute genes in Drosophila obscura
Samuel Lewis*, Darren Obbard
The University of Edinburgh, UK
P-2123 Robust Codon Usage in Protein Ligand Binding Sites
Tugce Bilgin*1,3, Isil Aksan Kurnaz4, Turkan Haliloglu5, Andreas Wagner1,2
1Institute of Evolutionary Biology and Environmental Sciences, University of Zurich, Switzerland, 2The Santa Fe Institute, USA, 3The Swiss Institute of Bioinformatics, Switzerland, 4Department of Genetics and Bioengineering, Yeditepe University, Turkey, 5Polymer Research Center, Bogazici University, Turkey
P-2262 Comparative transcriptomics without the aid of reference genomes.
Peter Harrison*1, Marie Pointer1,2, Judith Mank1
1University College London, UK, 2University of Oxford, UK
P-2189 The Evolutionary Consequences of Meiotic Recombination:New Insights from Double Strand Breaks in Mouse
Yves Clement*1, Laurent Duret2, Peter Arndt1
1Max Planck Institute for Molecular Genetics, Germany, 2UMR CNRS 5558 Laboratoire de Biométrie et Biologie Evolutive, France
P-2320 Evidence for birth-and-death evolution of a secondary metabolite biosynthetic gene cluster and its relocation within and between genomes of the filamentous fungus Fusarium
Robert Proctor1, François Van Hove2, Antonia Susca3, Gaetano Stea3, Mark Busman1, Theo van der Lee4, Cees Waalwijk4, Todd Ward*1, Antonio Moretti3
1U.S. Department of Agriculture, USA, 2Université catholique de Louvain, Belgium, 3National Research Council, Italy, 4Plant Research International, The Netherlands
P-2007 Matching minor allele frequency rectifies confounding effects of purifying selection on population differentiation measures
Takahiro Maruki*1, Jesse Taylor2
1Indiana University, USA, 2Arizona State University, USA
P-2321 Experimental Characterization of Urzymes Supports a Sense/Antisense Origin of Amino Acid Activation by Class I and II Aminoacyl-tRNA Synthetases
Charles Carter*, Li Li, Srinivas Niranj Chandrasekharan, Martha L. Collier
University of North Carolina at Chapel Hill, USA
P-2008 Estimated demographic parameters of modern human migration to the New World by whole mtDNA sequences of non-admixture Mesoamericans
Jun Gojobori*1, Shintaroh Ueda2
1Graduate School for Advanced Studies, Japan, 2The University of Tokyo, Japan
P-2009 Jaatha, a fast method to infer demographic parameters - not only for wild tomatoes
Lisha Mathew*1, Laura E. Rose2, Dirk Metzler1
1Ludwig-Maximilians-Universität, Germany, 2Heinrich-Heine-Universität, Germany
P-2322 Extensive intron gain in the ancestor of placental mammals
Dusan Kordis
Josef Stefan Institute, Department of Molecular and Biomedical Sciences, Slovenia
P-2263 Patterns of gene expression divergence and protein evolution in mammals
Maria Warnefors*1, Henrik Kaessmann1
1University of Lausanne, Switzerland, 2Swiss Institute of Bioinformatics, Switzerland
P-2010 Detecting and characterizing selection at loci subject to recurrent mutation.
Ryan Haasl*, Bret Payseur
University of Wisconsin - Madison, USA
P-2011 The joint effects of background selection and genetic recombination on local gene genealogies
Kai Zeng*1, Brian Charlesworth2
1University of Sheffield, UK, 2University of Edinburgh, UK
P-2323 Molecular evolutionary analysis of human AQP7 and the pseudogenes
Koyuru Inui*, Yoko Satta
The Graduate University for Advanced Studies (Sokendai), Japan
P-2190 Large genomic domains resulting from replication-associated mutational asymmetries are conserved since amniota divergence
Chun-Long Chen*1, Antoine Baker2, Benjamin Audit2, Arach Goldar3, Yves d'Aubenton-Carafa1, Guillaume Guilbaud4, Aurélien Rappailles4, Olivier Hyrien4, Alain Arneodo2, Claude Thermes1
1Centre de Génétique Moléculaire, CNRS, France, 2Laboratoire Joliot Curie, ENS Lyon, CNRS, France, 3CEA, iBiTecS, France, 4ENS Paris, UMR CNRS 8541, France
P-2124 Functional evolution of nociceptive receptors TRPA1 and TRPV1 in vertebrates
Shigeru Saito*1, Kazumasa Nakatsuka2, Masashi Ohkita2, Kenji Takahashi2, Naomi Fukuta1, Toshio Ohta2, Makoto Tominaga1,3
1Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences), Japan, 2Tottori University, Japan, 3The Graduate University for Advanced studies, Japan
P-2012 Genetic structure of spatially overlapping contact zones of two Iberian amphibians: a comparative approach
Helena Gonçalves1, Jesús Díaz-Rodríguez1,2, Alexandre Silva-Ferreira1,3, Tiago S. Neves1, Miguel Tejedo2, Iñigo Martínez-Solano4, Fernando Sequeira*1
1CIBIO/UP, Centro de Investigação em Biodiversidade e Recursos Genéticos da Universidade do Porto, Portugal, 2Departamento de Ecología Evolutiva, Estación Biológica de Doñana-CSIC, Spain, 3Departamento de Biologia, Faculdade de Ciências da Universidade do Porto, Portugal, 4Instituto de Investigación en Recursos Cinegéticos (CSIC-UCLM-JCCM), Spain
P-2231 Genetic variance-control in genome-wide network expression analyses.
Ronald Nelson*1, Xidan Li1, Xia Shen2, Örjan Carlborg1
1Swedish University of Agricultural Sciences, Sweden, 2Uppsala University, Sweden
P-2013 Private haplotypes as detectors for population-specific selection
Agnès Sjöstrand*1,2, Per Sjödin2,3, Mattias Jakobsson2
1MNHN, France, 2EBC, Uppsala University, Sweden, 3SLU, Sweden
P-2014 Inferring human population history from multiple genome sequences
Stephan Schiffels*, Richard Durbin
Wellcome Trust Sanger Institute, UK
P-2015 Signs of adaptation in interacting genes
Joséphine Daub*1,3, Marc Robinson-Rechavi2,3, Laurent Excoffier1,3
1University of Berne, Switzerland, 2University of Lausanne, Switzerland, 3Swiss Institute of Bioinformatics, Switzerland
P-2324 Genome-scale analyses of non-bilaterian metazoans clarify opsin evolution and the origin of vision in animals
Roberto Feuda*, Sinead Hamilton, James O. McInerney, Davide Pisani
N.U.I Maynooth, Ireland
P-2325 Evolutionary causes and consequences of losing key chaperone genes
Tobias Warnecke
Centre for Genomic Regulation, Spain
P-2016 A new haplotype test for the detection of selection signatures using data from multiple populations.
Maria Ines Fariello*, Magali SanCristobal, Simon Boitard, Bertrand Servin
INRA, France
P-2232 Interdomain transfer of an intein residing within the archaeal-type ATP synthase catalytic subunit.
J. Peter Gogarten*, Shannon M. Soucy, Kristen S. Swithers, Pascal Lapierre, David Williams
University of Connecticut, USA
P-2326 A non-cording DNA region is an origin of three primate orphan gene families on the sex chromosome.
Mineyo Iwase*1, Hielim Kim2, Naoyuki Takahata1, Yoko Satta1
1The Graduate University for Advanced Studies (Sokendai), Japan, 2The Pennsylvania State University, USA
P-2125 Genomics and physiology to investigate the lipid metabolism of 9 oleaginous yeasts
Stéphanie Michely*1, Claude Gaillardin2, Jean-Marc Nicaud3, Cécile Neuvéglise1
1INRA, UMR 1319 Micalis, France, 2AgroParisTech, Micalis, France, 3CNRS, Micalis, France
P-2233 Understanding the transcriptional gene regulation networks: a quantitative genetics approach
Murat Tugrul*, Tiago Paixao, Gasper Tkacik, Nick Barton
IST-Austria, Austria
Miguel Carneiro*1,7, Frank Albert5,6, José Melo-Ferreira1, Nicolas Galtier4, Philippe Gayral4, Jose Blanco-Aguiar2, Rafael Villafuerte62, Michael Nachman3, Nuno Ferrand1,7
1CIBIO-UP, Portugal, 2IREC, Spain, 3Department of Ecology and Evolutionary Biology, University of Arizona, USA, 4Institut des Sciences de l'Evolution Université Montpellier 2, France, 5Princeton University, USA, 6Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Germany, 7Departamento de Biologia, Faculdade de Ciências Universidade do Porto, Portugal
P-2126 Impact of the M. tuberculosis Genetic Background on the Acquisition of Drug Resistance-conferring Mutations 
Sonia Borrell*1, Graham Rose2, Julia Feldmann1, Sebastien Gagneux1
1Swiss Tropical and Public Health Institute. University of Basel., Switzerland, 2MRC National Institute for Medical Research., UK
P-2264 Conservation and function of noncoding RNAs in primate evolution
Courtney Babbitt*, Lisa Pfefferle, Olivier Fedrigo, Gregory Wray
Duke University, USA
P-2358 The inhibition of the S-RNase cytoxicity in Rosaceae: the Prunus 'one S-pollen gene' model and the Pyrinae 'non-self recognition by multiple S-pollen factors' model
Bruno Aguiar1, Jorge Vieira1, Nuno Fonseca2, Olivier Raspé3, Cristina Vieira*1
1Instituto de Biologia Molecular e Celular (IBMC), University of Porto, Portugal, 2CRACS-INESC Porto, Portugal, 3National Botanic Garden of Belgium, Belgium
P-2191 On the track of horizontally transferred sequences between two closely related species Drosophila melanogaster and Drosophila simulans.
Laurent MODOLO*, Emmanuelle LERAT
UMR CNRS 5558 Université Lyon1, France
P-2018 Inference of demographic history and natural selection in African Pygmy populations from whole-genome sequencing data
Martin Sikora*1, Etienne Patin2, Helio Costa1, Katherine Siddle2, Brenna M Henn1, Jeffrey M Kidd1,3, Ryosuke Kita1, Carlos D Bustamante1, Lluis Quintana-Murci2
1Department of Genetics, School of Medicine, Stanford Uni, USA, 2Unit of Human Evolutionary Genetics, Institut Pasteur, CNRS URA3012, France, 3Departments of Human Genetics and Computational Medicine and Bioinformatics, University of Michigan Medical School, USA
P-2019 On the prospect of identifying adaptive loci in recently colonized populations
Yu-Ping Poh*1,2, Vera Domingues2, Hopi Hoekstra2, Jeffery Jensen1,3
1UMass Medical School, USA, 2Harvard University, USA, 3EPFL, Switzerland
P-2265 Birth and functional evolution of mammalian microRNA genes
julien meunier*1, frédéric lemoine1, magali soumillon1, angelica lietchi1, manuela weier1, katerina guschanski1, haiyang hu1, philipp khaitovitch2, henrik kaessmann2
1University of Lausanne, Switzerland, 2Chinese Academy of Sciences, China
P-2192 Genome-wide copy number variation in African Pygmy hunter-gatherers and Bantu-speaking farmers.
Eddie Loh*1, Etienne Patin1, Katie Siddle1, Hélène Quach1, Christine Harmant1, Noémie Becker2, Béatrice Régnault3, Laure Lemée3, Jean-Marie Hombert4, Alain Froment2, Paul Verdu5, Luis Barreiro6, Nathaniel J. Dominy7, George Perry8, Evelyne Heyer2, Lluís Quintana-Murci1
1Human Evolutionary Genetics, CNRS URA3012, Institut Pasteur, France, 2Ecoanthropology and Ethnobiology, CNRS/MNHN/Université P7 UMR 5145, France, 3Genotyping Platform, Institut Pasteur, France, 4Département de Dynamique du Langage, CNRS UMR 5596, Université Lumière-Lyon 2, France, 5Department of Biology, Stanford University, USA, 6Université de Montréal, Centre de recherche CHU Sainte-Justine, Canada, 7Anthropology department, Dartmouth College, USA, 8Department of Human Genetics, University of Chicago, USA
P-2020 The story of wheat domestication and improvement as told by the nutrient content gene NAM-B1
Jenny Hagenblad
Linkoping University, Sweden
P-2021 1001 queens: spatial and temporal variation of kin structure in super-colonial ants
Eva Schultner*1, Jari Saramäki2, Heikki Helanterä1
1University of Helsinki, Finland, 2Aalto University, Finland
P-2234 Evolution of the Omp85 protein family and implications for outer membrane protein diversity
Eva Heinz*, Trevor Lithgow
Monash University, Australia
P-2327 Chemosensory protein gene family evolution in ants
Jonna Kulmuni*1,2, Yannick Wurm3, Pekka Pamilo4
1University of Oulu, Finland, 2Biocenter Oulu, Finland, 3Queen Mary, University of London, UK, 4University of Helsinki, Finland
P-2266 Accurate tracing of a transcriptome changes in the course of hybrid speciation
Till Czypionka*1, Jie Cheng1, Alexander E. Pozhitkov1,2, Arne W. Nolte1
1Max-Planck-Institute for Evolutionary Biology, Germany, 2Department of Periodontics, University of Washington, USA
Victoria Suarez-Ulloa1, Vanessa Aguiar-Pulido2, Rodrigo Gonzalez-Romero1, Ciro Rivera-Casas1, Juan Fernandez-Tajes1, Juan Ausio3, Josefina Mendez1, Julian Dorado2, Jose M. Eirin-Lopez*1
1CHROMEVOL-XENOMAR Group, Department of Cellular and Molecular Biology, University of A Coruna, Spain, 2RNASA-IMEDIR Group, Department of Information and Communication Technologies, University of A Coruna, Spain, 3Department of Biochemistry and Microbiology, University of Victoria, Canada
Jean-Baptiste Leducq*, Guillaume Charron, Guillaume Diss, Alexandre Dubé, Christian Landry
PROTEO – Institut de Biologie Intégrative et des Systèmes - Université Laval, Canada
P-2022 The effects of sweeps on surrounding loci in large populations
Daniel Weissman*, Nicholas Barton
IST Austria, Austria
P-2193 Analyses and computer simulations of hotspot distributions in human genome
Dorota Mackiewicz*1, Paulo Murilo Castro de Oliveira2, Suzana Moss de Oliveira2, Stanisław Cebrat1
1Faculty of Biotechnology, University of Wroclaw, Poland, 2Instituto de Física, Universidade Federal Fluminense, Brazil
P-2127 Functional retrogenes - identification and analysis.
Joanna Ciomborowska*, Michal Kabza, Kamil Sambor, Izabela Makalowska
Adam Mickiewicz University, Faculty of Biology, Laboratory of Bioinformatics, Poland
P-2023 An evolutionary history of the selectin gene cluster in humans
Rachele Cagliani*1, Matteo Fumagalli1, Marco Fracassetti1, Diego Forni1, Uberto Pozzoli1, G. Pietro Comi2, Federico Marini1, Nereo Bresolin1,2, Mario Clerici3, Manuela Sironi1
1Scientific Institute IRCCS E. Medea, Italy, 2Dino Ferrari Centre, Department of Neurological Sciences, University of Milan, Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico, Italy, 3Chair of Immunology, Department of Biomedical Sciences and Technologies LITA Segrate, University of Milan, Italy, 4Fondazione Don C. Gnocchi, IRCCS, Italy
P-2268 Rapid ecological speciation driven by selection on a small set of ‘adaptation' genes
Mark Chapman*, Dmitry Filatov
University of Oxford, UK
P-2359 A formal definition for syntenic blocks
Cristina G. Ghiurcuta*, Bernard Moret
EPFL, Switzerland
P-2269 Quantitative trait mapping of trans-regulatory factors associated with opsin gene expression in cichlid fishes
Kelly O'Quin*, Jane Schulte, Zil Patel, Matthew Conte, Karen Carleton
University of Maryland, USA
P-2024 Integration of selection signatures and GWAS data identifies novel susceptibility loci for Crohn's disease
Rachele Cagliani1, Diego Forni1, Uberto Pozzoli1, Andrea Cassinotti4, Matteo Fumagalli1, Matteo Giani1, Stefania Riva1, Rosanna Asselta6, Giacomo P Comi5, Nereo Bresolin5, Mario Clerici3,2, Manuela Sironi*1
1Scientific Institute IRCCS E. Medea, Italy, 2Don C. Gnocchi Foundation ONLUS, IRCCS, Italy, 3Department of Biomedical Sciences and Technologies LITA Segrate, University of Milan, Italy, 4L. Sacco University Hospital, Italy, 5Dino Ferrari Centre, Department of Neurological Sciences, University of Milan, Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico, Italy, 6Department of Biology and Genetics for Medical Science, University of Milan, Italy
P-2128 Amino acid polymorphism at Drosophila methuselah-like genes is associated with lifespan differences.
Micael Reis*, Ana Araújo, Bruno Aguiar, Helder Rocha, Cristina Vieira, Jorge Vieira
IBMC, Portugal
P-2328 The fate of S-RNase gene duplications in Rosaceae
Bruno Aguiar*1, Jorge Vieira1, Ana Cunha1, Nuno Fonseca2, Cristina Vieira1
1IBMC, Portugal, 2CRACS-INESC, Portugal
P-2173 Evolution of dFOXO binding sites in the Inslulin-like Receptor (InR) gene of Drosophila
Dorcas J. Orengo*, Montserrat Aguadé, Elvira Juan
Dept. Genètica, Univ. Barcelona, Spain
P-2270 Bgee, a database for the study of gene expression evolution
Frederic Bastian1,2, Julien Roux1,2, Anne Niknejad1,2, Aurelie Comte1,2, Sebastien Moretti1,2, Gilles Parmentier1,2, Marc Robinson-Rechavi*1,2
1University of Lausanne, Switzerland, 2Swiss Institute of Bioinformatics, Switzerland
P-2329 Role of low-complexity regions in protein formation and functional diversification
Núria Radó-Trilla*1, Macarena Toll-Riera1, Florian Martys1, M. Mar Albà1,2
1Evolutionary Genomics Group, Fundació Institut Municipal d’Investigació Mèdica (FIMIM)-Universitat Pompeu Fabra (UPF), Spain, 2Catalan Institution for Research and Advanced Studies (ICREA), Spain
P-2330 Context-dependent evolution of protein domains and their repeats
Dan Reshef*1, Liran Carmel2, Ora Schueler-Furman1
1Department of Microbiology and Molecular Genetics, Institute for Medical Research Israel-Canada, Hadassah Medical School, The Hebrew University of Jerusalem, Israel, 2Department of Genetics, The Alexander Silberman Institute of Life Sciences, Faculty of Science, The Hebrew University of Jerusalem, Israel
P-2025 North American Drosophila melanogaster produced by admixture between African and European populations: An Approximate Bayesian Computation approach
Pablo Duchen*, Stefan Laurent, Daniel Zivkovic, Wolfgang Stephan
University of Munich, Germany
P-2271 Evolutionary patterns of regulatory divergence in Drosophila
Joseph Coolon*1, C. Joel McManus2, Kraig Stevenson1, Brenton Graveley3, Patricia Wittkopp1
1University of Michigan, Department of Ecology and Evolutionary Biology, USA, 2Carnegie Mellon University, Department of Biological Sciences, USA, 3University of Connecticut Health Center, Department of Genetics and Developmental Biology, USA
P-2360 Not another alignment program paper: How to improve multiple alignments by selecting the appropiate isoform combination.
José Luis Villanueva-Cañas*2, M Mar Albà1,2
1Catalan Institution for Research and Advanced Studies, Spain, 2volutionary Genomics Group, Fundació Institut Municipal d’Investigació Mèdica (FIMIM)-Universitat Pompeu Fabra (UPF), Spain
P-2161 Duplications in Streamlined Apicomplexan Genomes
Jeremy DeBarry*, Jessica Kissinger
The University of Georgia, USA
P-2236 Reverse engineering the gap gene network in dipterans.
Anton Crombach*1, Karl Wotton1, Damjan Cicin-Sain1, Maksat Ashyralyyev2, Johannes Jaeger1
1Centre for Genomic Regulation (CRG), Spain, 2Bahçesehir Üniversitesi, Turkey
P-2194 Yeast evolution: comparative genomics of 10 Lachancea species
Véronique Sarilar*1, Jean-Philippe Meyniel2, Cécile Neuvéglise1
1INRA UMR1319, AgroParisTech, Institut Micalis, Biologie intégrative du métabolisme lipidique microbien, France, 2ISoft, Bioinformatic Team, France
P-2237 Efficient constraint-based metabolic modeling and optimization in R
Gabriel Gelius-Dietrich*, C. Jonathan Fritzemeier, Abdelmoneim Desouki, Martin J. Lercher
Heinrich-Heine-University, Germany
P-2026 Genetic structure in North African human populations and the gene flow to Southern Europe
Laura R Botigué1, Brenna M Henn2, Simon Gravel2, Jaume Bertranpetit1, Carlos D Bustamante2, David Comas*1
1Institut de Biologia Evolutiva (IBE, CSIC-UPF), Spain, 2Stanford University, USA
P-2272 Evolutionary Genomics of Plant Reproductive Isolation
Toni Gossmann*, Karl Schmid
University of Hohenheim, Germany
P-2027 The influence of natural selection in the antigen presentation pathway
Felix M Schulze*, Genís Parra, Cesare de Fillipo, Aida M Andrés
Max Planck Institute for Evolutionary Anthropology, Germany
P-2028 Genetic variability of Calvin cycle genes in accessions of Arabidopsis thaliana
Madlen Stange*, Sandra Schwarte, Fanny Wegner, Ralph Tiedemann
University of Potsdam, Germany
P-2366 Molecular evolution of the genes encoding the PRC2 and PhoRC Polycomb complexes in Drosophila.
Juan Manuel Calvo*, Montserrat Aguadé, Montserrat Papaceit, Carmen Segarra
Universitat de Barcelona, Spain
P-2238 A comprehensive census of horizontal gene transfers from prokaryotes to unikonts
Pere Puigbo*, Sergei Mekhedov, Yuri I. Wolf, Eugene V. Koonin
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, USA
P-2174 Evolutionary dynamics of MADS-box transcription factor binding sites in plants
Suzanne de Bruijn*1, Jose M Muino2, Gerco Angenent2, Kerstin Kaufmann1
1Wageningen University, laboratory for molecular biology, The Netherlands, 2Plant Research International, department Bioscience, The Netherlands
P-2029 Patterns of strong selective sweeps in Northern Swedish Arabidopsis thaliana
Christian Huber*1, Quan Long2, Magnus Nordborg2, Ines Hellmann1
1Max F. Perutz Laboratories, Austria, 2Gregor Mendel Institute of Molecular Plant Biology GmbH, Austria
P-2239 A system-level, molecular evolutionary analysis of mammalian phototransduction
Brandon Invergo*, Ludovica Montanucci, Hafid Laayouni, Jaume Bertranpetit
IBE-Institute of Evolutionary Biology (UPF-CSIC), CEXS-UPF-PRBB, Spain
P-2273 Genetic variants count for gene expression variability in human lymphoblastoid cells
James Cai
Texas A&M University, USA
P-2030 Salt tolerance in Arabidopsis thaliana: polymorphism and phenotypic response to salt stress
Eva Puerma*, Montserrat Aguadé
Universitat de Barcelona, Spain
P-2240 Homology Network Articulation Points Reveal Rosetta Stone Proteins
Leanne Haggerty*, James McInerney
NUI Maynooth, Ireland
P-2195 Estimating the rate of meiotic gene conversion rate in humans
Amy Williams*1,2, Nick Patterson1,2, Thomas Dyer3, John Blangero3, David Reich1,2
1Harvard Medical School, USA, 2Broad Institute of Harvard and MIT, USA, 3Texas Biomedical Research Institute, USA
P-2196 Expanded phylogenetic analysis of the telomere-associated transposable element, HeT-A, in Drosophila.
Jonathan Clark*, Haylie Cox
Weber State University, USA
P-2129 Why have sex? Mutational meltdown in asexual organisms
Philipp H. Schiffer*, Einhard Schierenberg
Institute for Zoology, University of Cologne, Germany
P-2031 Identification of Soft Sweeps in the Drosophila melanogaster Genome
Nandita Garud*, Philipp Messer, Dmitri Petrov
Stanford University, USA
P-2122 Purifying and positive selection in the Medicago truncatula genome
Timothy Paape*1, Peng Zhao1, Thomas Batiallon2, Nevin Young1, Peter Tiffin1
1University of Minnesota, USA, 2University of Denmark-Aarhus, Denmark
P-2197 The Plant Proteome Folding Project : Structure and Positive Selection in Plant Protein Families
Melissa Pentony*1, Patrick Winters1, Duncan Penfold-Brown1, Kevin Drew1, Apurva Narechania2, Rob DeSalle2, Richard Bonneau1, Michael Purugganan1
1New York University, USA, 2American Museum of Natural History, USA
P-2361 Indel Reliability in Phylogenetic Inference
Haim Ashkenazy*1, Ofir Cohen1, Dorothée Huchon2, Tal Pupko1
1Department of Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Israel, 2Department of Zoology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Israel
P-2274 Transcriptomic resilience to global warming in the seagrass Zostera marina, a marine foundation species
Susanne U. Franssen*1, Jenny Gu1, Nina Bergmann2, Gidon Winters2, Ulrich C. Klostermeier3, Philip Philip Rosenstiel3, Erich Bornberg-Bauer1, Thorsten B.H. Reusch2
1Institute for Evolution and Biodiversity, University of Münster, Germany, 2Evolutionary Ecology of Marine Fishes, Leibniz-Institute for Marine Sciences, Germany, 3Institute of Clinical Molecular Biology, Christian-Albrechts-University, Germany
P-2331 Duplication dynamics and functional innovation in the Rab family of small GTPases
Yoan Diekmann*, Jose B. Pereira Leal
Instituto Gulbenkian de Ciência, Portugal
P-2130 A Screen for QTLs that Influence the Degree of Morphological Variation in Natural Yeast Isolates
Kerry Geiler-Samerotte*, Naomi Ziv, Mark Siegal
New York University, USA
P-2131 Genetic response of Daphnia pulicaria to historic pH changes in lakes
Billy Culver*1,2, Philip Morton2, Dagmar Frisch2, Lawrence Weider1,2
1University of Oklahoma, USA, 2University of Oklahoma Biological Station, USA
P-2032 Genome-wide effects of sex-specific hybrid incompatibility on neutral introgression
Marcy Uyenoyama*, Seiji Kumagai, Liuyang Wang
Duke University, USA
P-2275 The origins and evolution of long non-coding RNAs in tetrapods
Anamaria Necsulea*1,2, Magali Soumillon1,2, Angélica Liechti1,2, Manuela Weier1,2, Henrik Kaessmann1,2
1University of Lausanne, Switzerland, 2Swiss Institute of Bioinformatics, Switzerland
P-2033 Estimating a date of mixture of ancestral South Asian populations
Priya Moorjani*1,2, Nick Patterson2, Periasamy Govindaraj3, Danish Saleheen4, John Danesh4, Lalji Singh*3,5, Kumarasamy Thangaraj*3, David Reich*1,2
1Harvard University, USA, 2Broad Institute, USA, 3Centre for Cellular and Molecular Biology, India, 4Dept of Public Health and Care, University of Cambridge, UK, 5Genome Foundation, India
P-2198 Relative rates of evolution among the three genetic compartments of the red alga Porphyra differ from those of land plants and green algae
David Smith*1, Jimeng Hua2, Robert Lee2, Patrick Keeling1
1University of British Columbia, Canada, 2Dalhousie University, Canada
P-2034 Extreme (X)-QTL Mapping Seed and Seedling Traits in Arabidopsis thaliana
Wei Yuan*, Michael Purugganan
New York University, USA
P-2132 Evolving on phenotype landscapes
Jose A Cuesta*1, Susanna C Manrubia2
1Universidad Carlos III de Madrid, Spain, 2Centro de Astrobiología (INTA-CSIC), Spain
P-2175 Selection on noncoding DNA in the Brassicaceae
Annabelle Haudry*1,2, Adrian Platts3, Stephen I. Wright2, Robert Williamson2, Emilio Vello3, Paul Harrison3, Thomas Bureau3, Alan Moses2, Mathieu Blanchette3
1University of Lyon, France, 2University of Toronto, Canada, 3McGill University, Canada
P-2276 Next-generation insights into a classic evolutionary system and the development of SenecioDB
Owen Osborne*1, Thomas Batstone2, Simon Hiscock2, Dmitry Filatov1
1University of Oxford, UK, 2University of Bristol, UK
P-2367 Genome-wide usage of accurately translated codons tracks a tRNA modification across the Drosophila phylogeny
John Zaborske1, Vanessa Bauer DuMont2, Tao Pan1, Charles Aquadro2, D. Allan Drummond*1
1University of Chicago, USA, 2Cornell University, USA
P-2162 Evaluating the Ortholog Conjecture using the Structure Function Linkage Database
Kimmen Sjolander*1, Patricia Babbitt2
1University of California Berkeley, USA, 2University of California San Francisco, USA
P-2241 The origin and evolution of the melanopsin gene family: the OPN4x and OPN4m paralogs
Rui Borges*1,2, Vítor Vasconcelos1,2, Agostinho Antunes1,2
1CIIMAR, Portugal, 2FCUP, Portugal
P-2035 Long-term balancing selection may be more common than previously believed: several examples from apes
Ellen M. Leffler*1, Ziyue Gao1, Susanne Pfeifer2, Laure Ségurel1, Adam Auton3, Ryan Hernandez4, Joanna L. Kelley7, Jeffrey Kidd7, S. Cord Melton1, Laurie Stevison4, Aarti Venkat1, Oliver Venn3, Ronald Bontrop6, Carlos Bustamante7, Michael Hammer8, Jeffrey Wall4, Peter Donnelly2,3, Gilean McVean2,3, Molly Przeworski1,5
1University of Chicago, USA, 2University of Oxford, UK, 3Wellcome Trust Centre for Human Genetics, UK, 4University of California, San Francisco, USA, 5Howard Hughes Medical Institute, USA, 6Biomedical Primate Research Centre, The Netherlands, 7Stanford University, USA, 8University of Arizona, USA
P-2133 Why do so many fungal open reading frames contain repeats?
Jan Schmid*1, Matt Wilkins2, Ningxin Zhang1, Rosie Bradshaw1, Murray Cox1, Richard Cannon3, Chris Schardl4
1Massey University, New Zealand, 2Scientific Consulting, New Zealand, 3University of Otago, New Zealand, 4University of Kentucky, USA
P-2199 Genomic Modification in Bdelloid Rotifers Following Full-Body Desiccation and DNA Repair
Norian Caporale-Berkowitz*1, Bette Hecox-Lea2,3, David Mark Welch1,2
1Brown University, USA, 2Marine Biological Laboratory, USA, 3Northeastern University, USA
P-2134 Rapid evolution in lipid and metabolic composition of the human brain
Kasia Bozek*1, Patrick Giavalisco2, Philipp Khaitovich1
1Partner Institute for Computational Biology MPG-CAS, China, 2Max Planck Institute of Molecular Plant Physiology, Germany
P-2002 Diversity of endogenous retroviruses in the saltwater crocodile (Crocodylus porosus) in the Northern Territory of Australia
Amanda Y. Chong*1, Sarah Atkinson1, Sally Isberg1,2, Lorna Melville3, Jaime Gongora1
1University of Sydney, Faculty of Veterinary Science, Australia, 2Porosus Pty Ltd, Australia, 3OIC Berrimah Veterinary Laboratories Department of Resources, Australia
P-2036 A computational approach to detect population structure and signatures of local adaptation from high-throughput re-sequencing data
Matteo Fumagalli*1, Thorfinn Korneliussen2, Tyler Linderoth1, Anders Albrechtsen2, Rasmus Nielsen1,2
1University of California, USA, 2University of Copenhagen, Denmark
P-2277 A comparison of brain transcriptomes in domesticated and wild animals
Frank W. Albert*1,2, Mehmet Somel3, Miguel Carneiro4, Ayinuer Aximu1, Michel Halbwax1, Olaf Thalmann5, Jose A. Blanco-Aguiar4,7, Irina Plyusnina6, Lyudmila Trut6, Rafael Villafuerte7, Nuno Ferrand4, Sylvia Kaiser8, Per Jensen9, Svante Pääbo1
1Max Planck Institute for Evolutionary Anthropology, Germany, 2Princeton University, USA, 3University of California Berkeley, USA, 4University of Porto, Portugal, 5University of Turku, Finland, 6Siberian Branch of the Russian Academy of Sciences, Russia, 7Instituto de Investigación en Recursos Cinegéticos, Spain, 8University of Münster, Germany, 9Linköping University, Sweden
P-2135 Medaka (Oryzias latipes) as a population model for studying functional differences between the alleles of human polymorphisms
Takafumi Katsumura*1,2, Shoji Oda1, Hiroshi Mitani1, Shoji Kawamura1, Hiroki Oota1,2
1University of Tokyo, Japan, 2Kitasato University School of Medicine, Japan
P-2278 Shifting fitness consequence of variation in LCB2 gene expression in yeast
Joshua Rest*1, Christopher Morales1, John Waldron1, Dana Opulente1, Julius Fisher1, Seungjae Moon1,2, Kevin Bullaughey3, Lucas Carey4, Demitri Dedousis1
1Stony Brook University, USA, 2Weill Cornell Graduate School of Medical Science, USA, 3University of Chicago, USA, 4Weizmann Institute of Science, Israel
P-2279 How to survive over the winter on northern latitudes? Cold acclimation in two Drosophila species with different distributions - a comparative genomic approach
Maaria Kankare*1, Laura Vesala1, Tiina Salminen1, Asta Laiho2, Anneli Hoikkala1
1University of Jyvaskyla, Finland, 2Finnish Microarray and Sequencing Centre, Finland
P-2037 Long IBD in Europeans and recent population history
Peter Ralph*, Graham Coop
UC Davis, USA
P-2038 Fine-scale mapping complex signatures of positive selection in the human genome
Leslie Emery*, Joshua Akey
University of Washington Department of Genome Sciences, USA
P-2039 Heterozygote advantage as a natural consequence of adaptation in diploids
Diamantis Sellis*1, Benjamin Callahan2, Dmitri Petrov1, Philipp Messer1
1Department of Biology, Stanford University, USA, 2Department of Applied Physics, Stanford University, USA
P-2000 Can we understand bacterial evolution from MLST data?
Ferran Palero1,2, Fernando Gonzalez-Candelas*1,2
1University of Valencia, Spain, 2CSISP, Spain
P-2040 Signals of positive selection in North African human populations
Laura R. Botigué*1, Brenna M. Henn2, David Comas1, Carlos D. Bustamante2
1IBE (UPF-CSIC), Spain, 2Department of Genetics, Stanford University, USA
P-2003 Widespread interspecific divergence in cis-regulation of transposable elements in the Arabidopsis genus
Fei He1, Justin Borevitz2, Juliette de Meaux*1
1IEB, Germany, 2University of Chicago, USA
P-2136 Amino acid substitution regime is dependent upon the protein interaction mode with the GroEL chaperone
Judith Ilhan*, Giddy Landan, Tal Dagan
Institute for Molecular Evolution, Germany
P-2041 Gene flow between human populations during the exodus from Africa, and the timeline of recent human evolution
Aylwyn Scally*, Richard Durbin
Wellcome Trust Sanger Institute, UK
P-2200 Global characterization of polymorphic inversions in the human genome
Mario Cáceres*1,2, Alexander Martínez-Fundichely2, Cristina Aguado2, David Vicente2, Meritxell Oliva2, David Izquierdo2, Sergi Villatoro2, Marta Puig2, José Ignacio Lucas-Lledó2, Xavier Estivill3, Juan R. González4, Sònia Casillas2
1Institució Catalana de Recerca i Estudis Avançats (ICREA), Spain, 2Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, Spain, 3Center for Genomic Regulation (CRG-UPF), Spain, 4Center for Research in Environmental Epidemiology (CREAL), Spain
P-2042 Adaptation to urban environments in Arabidopsis thaliana
Angela Hancock*1,2, Felice Sperone2, Joy Bergelson2
1University of Vienna, Austria, 2University of Chicago, USA
P-2332 Non-neutral evolution of fatty acid desaturase F pseudogenes in Drosophila
Shun-Chern Tsaur1, Kuang-Hsi Chu2, Wei-Chin Ho2, Wan-Ju Shen3, Kevin Wei3, Chau-Ti Ting2,4, Shu Fang*3
1Department of Life Sciences & Institute of Genome Sciences, National Yang-Ming University, Taiwan, 2Institute of Zoology, National Taiwan University, Taiwan, 3Biodiversity Research Center, Academia Sinica, Taiwan, 4Department of Life Science & Institute of Ecology and Evolutionary Biology, National Taiwan University, Taiwan
P-2333 Adaptation and evolution of the olfactory subgenome in mammals
Graham Hughes*, Des Higgins, Emma Teeling
University College Dublin, Ireland
P-2137 Topological structure of the space of phenotypes: The case of RNA neutral networks
Jacobo Aguirre1, Javier M. Buldú2, Michael Stich1, Susanna C. Manrubia*1
1Centro de Astrobiología (INTA-CSIC), Spain, 2Complex Systems Group, Universidad Rey Juan Carlos, Spain
P-2043 Inference in the extinction/recolonisation model
Nick Barton2, Alison Etheridge3, Jerome Kelleher*1, Amandine Veber4
1University of Edinburgh, UK, 2IST Austria, Austria, 3University of Oxford, UK, 4Ecole Polytechnique, France
P-2163 Ortho-Gen: The ortholog dataset constructing tool for phylogenetic analysis
Tokumasa Horiike*1, Ryoichi Mimai1, Daisuke Miyata1,2, Yoshio Tateno1,3
1Shizuoka University, Japan, 2Chiba University of Commerce, Japan, 3Pohang University of Science and Technology, Republic of Korea
P-2334 Identification of potential chemosensory gene families in funnel web spiders using NGS
Cristina Frias-Lopez*1, Francisca C. Almeida1, Sara Guirao-Rico2, Miquel Arnedo3, Julio Rozas1
1Universitat de  Barcelona, Departament de Genètica, Spain, 2University of Edinburgh, Institute of Evolutionary Biology, UK, 3Universitat de Barcelona, Departament de Biologia Animal, Spain
P-2201 Indels and the evolution of genome architecture: The long and short of it
Erika Kvikstad*, Laurent Duret
University Lyon 1, France
P-2044 Long-term presence versus recent admixture: Bayesian and approximate-Bayesian analyses of genetic diversity of human populations in Central Asia
Friso Palstra*, Evelyne Heyer, Frederic Austerlitz
Eco-anthropologie et Ethnobiologie UMR 7206 CNRS, Equipe Genetique des Populations Humaines, Museum National d'Histoire Naturelle, France
P-2045 Demography and natural selection in chimpanzee populations inferred from full exome sequencing
Christina Hvilsom2,3, Jinjie Duan1, Thomas Bataillon1, Yingrui Li4, Thomas Mailund1, Kasper Munch1, Yu Qian1, Asger Hobolth1, Jun Wang4, Hans R. Siegismund2, Mikkel H. Schierup*1
1Aarhus University, Denmark, 2University of Copenhagen, Denmark, 3Copenhagen Zoo, Denmark, 4BGI, China
P-2046 Patterns of genetic diversity across the European rabbit (Oryctolagus cuniculus) hemoglobin beta (HBB) cluster suggest a recent and incomplete selective sweep at the HBB gene
Rita Campos*1,2, Nuno Ferrand1,2
1CIBIO - Centro de Investigacao em Biodiversidade e Recursos Geneticos, Portugal, 2Departamento de Biologia, Faculdade de Ciências da Universidade do Porto, Portugal
P-2368 PRDM9 binding targets occur within most human recombination hotspots
Nudrat Noor*2, Alexandru Aricescu1, Julian Knight2, Gil McVean1,2, Simon Myers1,2
1Department of Statistics, UK, 2Wellcome Trust Centre for Human Genetics, UK, 3Division of Structural Biology, Wellcome Trust Centre for Human Genetics, UK
P-2047 How the colonization of subantarctic islands shaped mouse populations
Anna Lorenc*1, Ines Hellmann2, Emilie Hardouin1, Diethard Tautz1
1MPI for Evolutionary Biology, Germany, 2MaBS at MFPL, Austria
P-2280 Detection of dual coding regions in mRNAs using ribosomal profiling data.
Audrey M. Michel*1, Kingshuk Roy Choudhury1, Andrew E. Firth2, Nicolas T. Ingolia3, John F. Atkins1, Pavel V. Baranov1
1University College Cork, Ireland, 2University of Cambridge, UK, 3Carnegie Institution for Science, USA
P-2242 Networks of Polynesian Language Evolution Reveal Frequent Word Borrowing Across the Islands 
Shijulal Nelson-Sathi*1, Simon Greenhill2, Russell D. Gray2, Tal Dagan1, William F. Martin1
1Institute of Molecular Evolution, Germany, 2Department of Psychology, New Zealand
Jose Sergio Hleap*1,2, Christian Blouin1
1Dalhousie University, Canada, 2Fundación SQUALUS, Colombia
P-2164 A Transcript Perspective on Evolution
Yann Christinat*, Bernard Moret
EPFL, Switzerland
P-2225 Detecting change in speciation and extinction rates with phylogenetic trees
Sacha Laurent*1,2, Marc Robinson-Réchavi1,2, Nicolas Salamin1,2
1University of Lausanne, Switzerland, 2Swiss Institute of Bioinformatics, Switzerland
P-2335 High prevalence of positive selection in rodent gene duplicates evolving both symmetrically and asymmetrically
Cinta Pegueroles*1, M. Mar Albà1,2
1Evolutionary Genomics Group, Fundació Institut Municipal d’Investigació Mèdica (FIMIM)-Universitat Pompeu Fabra (UPF), Spain, 2Catalan Institution for Research and Advanced Studies (ICREA), Spain
P-2336 Positive selection and diversification of the V1R gene family in strepsirrhine primates
Nick Mundy*1, Philipp Kappel1,2, Ute Radespiel2
1University of Cambridge, UK, 2University of Hannover, Germany
P-2139 Estimating the rate of irreversibility in protein evolution
Onuralp Soylemez*1, Fyodor Kondrashov1,2
1Center for Genomic Regulation, Spain, 2Institució Catalana de Recerca i Estudis Avançats (ICREA), Spain
P-2140 Molecular evolution of immune genes in socially diverse bees
Lumi Viljakainen*1, Brielle J. Fischman2, S. Hollis Woodard2, Gene E. Robinson2, Andrew G. Clark3
1University of Oulu, Finland, 2University of Illinois at Urbana-Champaign, USA, 3Cornell University, USA
P-2337 Molecular evolution and divergence of vertebrate heat shock factors
Kalle Rytkönen
University of Turku, Finland
P-2165 Building Structure-based Classification from Multiple Sequence Alignment with the T-RMSD method
Cedrik Magis*1,2, Cedric Notredame1,2
1Center for Genomic Regulation (CRG), Spain, 2Universitat Pompeu Fabra (UPF), Spain
P-2380 Multiple sequence alignment over-optimization bias impact downstream on population statistics and inferred phylogeny.
Abhijeet Shah*, Dirk Metzler
University of Munich, Germany
P-2166 Gene function prediction in plant genomes from large scale phylogenomics analyses
Mathieu Rouard*1, Jean-François Dufayard2, Valentin Guignon1, Mathieu Conte4, Anne-Muriel Arigon3, Vincent Berry3
1Bioversity International, Commodities for Livelihood Programme, France, 2Cirad, Department BIOS, UMR DAP, France, 3MAB, LIRMM, CNRS, Université Montpellier, France, 4SYNGENTA Seeds SAS, France
P-2243 Are changes in lifestyle associated with bursts of HGT in proteobacteria?
Thomas Laubach*, Martin J. Lercher
Heinrich-Heine-University Duesseldorf, Germany
P-2202 Copy Number Variation in the Porcine Genome
Yogesh Paudel*, Hendrik-Jan Megens, Ole Madsen, Mirte Bosse, Laurent Frantz, Richard Croojimans, Martien A.M. Groenen
Animal Breeding and Genomics Centre, Wageningen University, The Netherlands
P-2141 Mapping the evolutionary fitness landscape of C4 photosynthesis
David Heckmann*, Martin J. Lercher
Institute for Computer Science, HHU Düsseldorf, Germany
P-2281 Long term evolutionary adaptation of yeast to a fluctuating environment
Riddhiman Dhar*, Rudolf Sägesser, Christian Weikert, Andreas Wagner
Institute of Evolutionary Biology and Environmental Studies, University of Zurich, Switzerland
P-2048 Polymorphism Pattern of a MITE Locus Downstream of the Domestication Gene Teosinte-Branched1 in Wild and Cultivated Pearl Millet
Yann Dussert*1, Marie-Stanislas Remigereau2, Fontaine Michaël1,3, Alodie Snirc1, Ghayas Lakis1, Solenn Stoeckel4, Thierry Langin5, Aboubakry Sarr1, Thierry Robert1
1Ecologie, Systématique et Evolution, UMR 8079, Univ. Paris Sud, France, 2University of Southern California Molecular & Computational Biology, USA, 3Eco-Anthropologie et Ethnobiologie, UMR 7206 CNRS, MNHN, Univ. Paris Diderot, France, 4INRA, UMR 1099, Biology of Organisms and Populations applied to Plant Protection, France, 5INRA, UMR 1095, Génétique, Diversité et Ecophysiologie des Céréales, France
P-2142 Impact of selection on genes involved in regulatory network: a modelling study.
Frederic Austerlitz*1,2, Bénédicte Rhoné2, Jean-Tristan Brandenburg1,2
1Laboratoire Eco-Anthropologie et Ethnobiologie, UMR 7206 CNRS/MNHN/Université Paris 7, France, 2Laboratoire Ecologie, Systématique et Evolution, UMR 8079 CNRS/Université Paris-Sud/AgroParisTech, France
P-2282 Studying patterns of genetic variation in long non coding RNAs along the Great Ape lineage
Marta Melé*1,2, Roderic Guigó2, Tomàs Marquès1
1IBE, Spain, 2CRG, Spain
P-2049 Assessing the molecular evolution of the invasive bivalve Corbicula fluminea in Portugal
Cidália Gomes*1,2, Vítor Vasconcelos1,3, Lúcia Guilhermino1,2, Agostinho Antunes1,3
1CIMAR/CIIMAR, Centro Interdisciplinar de Investigação Marinha e Ambiental, Universidade do Porto, Portugal, 2ICBAS - Instituto de Ciências Biomédicas de Abel Salazar, Departamento de Estudos de Populações, Laboratório de Ecotoxicologia, Portugal, 3FCUP - Faculdade de Ciências da Universidade do Porto, Departamento de Biologia, Portugal
P-2050 Genetic variation in Drosophila subobscura: a multilocus analysis along chromosome J
Roser Pratdesaba*, Carmen Segarra, Montserrat Aguadé
Universitat de Barcelona, Spain
P-2203 Structured variations in intron/exon architecture according to gene intron number in two angiosperm species
Adrienne Ressayre*1,2, Pierre Montalent1,2, Christine Dillmann2, Johann Joets1,2
1INRA, France, 2Université Paris-Sud, France
P-2283 Sox duplicate evolution and constraints from molecular properties
Emilien Voldoire*, Frédéric Brunet, Jean-Nicolas Volff, Delphine Galiana-Arnoux
The Institute of Functional Genomics of Lyon, ENS de Lyon, France
P-2226 And another paradigm bites the dust: rooted global phylogeny
Ajith Harish*, Anders Tunlid, Charles Kurland
Lund University, Sweden
P-2051 Signs for balancing selection in S. paradoxus
Na Gao*, Martin J. Lercher
Institute for Computer Science Heinrich-Heine-University Duesseldorf, Germany
P-2052 The role of epistasis on the response to selection
Tiago Paixao*, Nick Barton
IST Austria, Austria
P-2244 Protein-Chaperone Connectivity in Yeast and Protein Ancestry
David Bogumil*1, David Alvarez-Ponce2, Giddy Landan1, James McInerney2, Tal Dagan1
1Institute of Molecular Evolution, Heinrich-Heine University, Germany, 2Department of Biology, National University of Ireland, Ireland
P-2362 Disentangling the phylogenetic signal carried by alignment gaps and guide trees
Salvador Capella-Gutíerrez, Toni Gabaldón*
Centre for Genomic Regulation (CRG), Spain
P-2176 In pursuit of functional nucleotides: Molecular mechanisms and fine-scale functional testing of noncoding sequences that contribute to pigmentation divergence in Drosophila.
Arielle Cooley*, Lisa Sramkoski, Wesley McLaughlin, Brad Lankowsky, Patricia Wittkopp
University of Michigan, USA
P-2284 Population and sex differences in Drosophila brain gene expression
Ana Catalan*, John Parsch
LMU, Germany
P-2356 Patterns of KLK2 and KLK3 diversity in Cercopithecoidea
Patrícia Marques*1,2, Rui Bernardino3, Teresa Fernandes3, Víctor Quesada2, Susana Seixas1, Belen Hurle4
1Institute of Molecular Pathology and Immunology of the University of Porto, Portugal, 2Department of Biochemistry and Molecular Biology, University of Oviedo, Spain, 3Lisbon Zoo Veterinary Hospital, Portugal, 4Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, USA
P-2053 The WFDC locus: a preferred target of natural selection in humans
Zelia Ferreira*1,2, Susana Seixas2, Aida Andres1, Warren Kretzschmar1, Jim Mullikin4, Pedro Cruz4, Praveen Cherukuri4, Eric Green1,4, NISC Comparative Sequencing Program1,4, Belen Hurle1
1National Human Genome Research Institute (NHGRI), USA, 2Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Portugal, 3Department of Zoology and Anthropology, Faculty of Sciences, University of Porto, Portugal, 4NIH Intramural Sequencing Center (NISC), USA
P-2355 The enigma of cADPR/NAADP calcium messenger biosynthesis and the limited taxonomic distribution of the ADP-ribosyl cyclases by computational multi-genome survey
Enza Ferrero*, Nicola Lo Buono, Fabio Malavasi
University of Torino, Italy
P-2363 Measuring the distance between multiple sequence alignments
Benjamin Blackburne*, Simon Whelan
University of Manchester, UK
P-2338 Evolutionary analysis and natural selection in betaine homocysteine methyltransferase (BHMT) and BHMT2 genes
Radhika Ganu, Yasuko Ishida, Alfred Roca*, Timothy Garrow, Lawrence Schook
University of Illinois at Urbana-Champaign, USA
Emilie Hardouin*, Diethard Tautz
Max Planck Institute for Evolutionary Biology, Germany
P-2245 The molecular basis of rapid temperature-driven divergence in European grayling (Thymallus thymallus) as revealed by shotgun proteomics
Spiros Papakostas*1, Mei Ning2, Asbjørn Vøllestad3, Craig Primmer1, Erica Leder1, Matthieu Bruneaux1
1University of Turku, Finland, 2Institute for Nutritional Sciences, China, 3University of Oslo, Norway
P-2204 The Drosophila buzzatii Genome Project
Yolanda Guillén*1, Nuria Rius1, Alejandra Delprat1, Marta Puig1, Alfredo Ruiz1, Sònia Casillas2, Miquel Ràmia2, Antonio Barbadilla2, Gisela Mir3, Jordi Garcia-Mas3, Ivo Gut4, Jordi Camps4, David Torrens5, Valentí Moncunill5, Andrew G. Clark6, Robert L. Unckless6, Cedric Feschotte7, Aurelie Kapusta7
1Departament de Genètica i de Microbiologia, Universitat Autònoma de Barcelona, Spain, 2Plataforma Bioinformàtica de la UAB, Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, Spain, 3Centre for Research in Agricultural Genomics (CRAG), Campus UAB, Edifici CRAG, Spain, 4Parc Científic de Barcelona, Centro Nacional de Análisis Genómico (CNAG), Torre I, Baldiri Reixac 4, Spain, 5Barcelona Supercomputing Center (BSC), Edifici TG (Torre Girona), Jordi Girona 31, Spain, 6Department of Molecular Biology and Genetics, Cornell University, USA, 7Department of Biology, University of Texas at Arlington, USA
P-2055 Characterizing adaptively relevant alleles in wild mice (Mus musculus L.)
Natascha Hasenkamp*, Diethard Tautz
Max Planck Institute for Evolutionary Biology, Germany
P-2246 Evolutionary analysis of innate immune system network in human and mouse marries phenotype and genotype.
Andrew Webb*, Claire Morgan, Thomas Walsh, Mary O’Connell
Dublin City University, Ireland
P-2285 The Evolutionary Significance of Y-linked Regulatory Variation in Drosophila
Timothy Sackton*1, Jun Zhou1, Bernardo Lemos2, Daniel Hartl1
1Harvard University, USA, 2Harvard School of Public Health, USA
P-2286 Molecular analysis of the mechanisms involved in THBS4 differential gene-expression in the human brain
Raquel Rubio-Acero*1, James W. Thomas2, Todd M. Preuss3, Mario Cáceres1,4
1Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, Spain, 2NIH Intramural Sequencing Center, National Human Genome Research Institute (NHGRI), National Institutes of Health (NIH), USA, 3Division of Neuroscience and Center for Behavioral Neuroscience, Yerkes National Primate Research Center, Emory University, USA, 4Institució Catalana de Recerca i Estudis Avançats (ICREA), Spain
P-2143 Studying the indirect impact of intrachromosomalrearrangements on the genome structure of microbes
Stephan Fischer*1,3, Carole Knibbe1,4, Samuel Bernard2,4, Guillaume Beslon1,3
1Inria Beagle Team, France, 2Inria Dracula Team, France, 3INSA-Lyon, France, 4Université Lyon I, France
P-2205 Simulating evolutionary scenarios to test whether they can induce reductive evolution
Berenice Batut*1,2, Mathilde Dumond1, Gabriel Marais2, Guillaume Beslon1, Carole Knibbe1
1INRIA Beagle Team, France, 2BGE Team (LBBE), France
P-2339 The evolutionary dynamics of Ppp1 catalytic subunits in the Metazoan
Susana Pereira*1, Vítor Vasconcelos1,2, Agostinho Antunes1,2
1CIIMAR, Centro Interdisciplinar de Investigação Marinha e Ambiental, Universidade do Porto, Portugal, 2Departamento de Biologia, Faculdade de Ciências, Universidade do Porto, Portugal
P-2144 How evolvable are polarization machines?
Liedewij Laan*, Andrew Murray
Fas Institute for Systems Biology, Harvard University, USA
P-2379 Inter-and Intra-specific morphological variation and scaling of microtubule derived-organelles
Beatriz F. Gomes*, José B. Pereira-Leal
Instituto Gulbenkian de Ciência, Portugal
P-2287 Life at Extremes: Molecular Adaptations of the Protist Halocafeteria to Hypersaline Environments
Tommy Harding*, Alastair G. B. Simpson, Andrew J. Roger
Dalhousie University, Canada
P-2206 Evolutionary Genomics of The Hedgehog Gene Family in Metazoans: Identification of The Desert Hedgehog Gene on Avian Genomes
Joana Pereira*1, Warren E. Johnson2, Stephen J. O’Brien2, Vitor Vasconcelos1,3, Agostinho Antunes1,2
1CIMAR/CIIMAR, Centro Interdisciplinar de Investigação Marinha e Ambiental, Universidade do Porto, Portugal, 2Laboratory of Genomic Diversity, National Cancer Institute, USA, 3Departamento de Biologia, Faculdade de Ciências, Universidade do Porto, Portugal
P-2056 Robust estimates of heterozygosity from low coverage sequencing data
Katarzyna Bryc*1, Nick Patterson2, David Reich1,2
1Harvard Medical School, USA, 2Broad Institute, USA
P-2057 Population structure and evidence of selection in the Khoe-San and Coloured populations from southern Africa
Carina Schlebusch*1, Pontus Skoglund1, Per Sjödin1, Lucie Gattepaille1, Sen Li1, Flora Jay2, Dena Hernandez3, Andrew Singleton3, Michael Blum2, Himla Soodyall4,5, Mattias Jakobsson1
1Uppsala University, Sweden, 2Université Joseph Fourier, France, 3National Institute on Aging (NIH), USA, 4University of the Witwatersrand, South Africa, 5National Health Laboratory Service, South Africa
P-2058 Impacts of life-style on human evolutionary history: A genome-wide comparison of herder and farmer populations in Central Asia
Michael C. Fontaine*1,2, Laure Segurel2,3, Christine Lonjou4, Tatiana Hegay5, Almaz Aldashev6, Evelyne Heyer2, Frederic Austerlitz1,2
1Ecology, Systematics & Evolution. UMR8079 Univ. Paris Sud - CNRS - AgroParisTech, France, 2Eco-Anthropologie et Ethnobiologie, UMR 7206 CNRS, MNHN, Univ Paris Diderot, Sorbonne Paris Cité, France, 3Department of Human Genetics, University of Chicago, USA, 4C2BiG (Centre de Bioinformatique/Biostatistique Génomique d’Ile de France), Plateforme Post-génomique P3S, Hôpital Pitié Salpêtrière, France, 5Uzbek Academy of Sciences, Institute of Immunology, Uzbekistan, 6Institute of Molecular Biology and Medicine, National Center of Cardiology and Internal Medicine, Kyrgyzstan
P-2145 Functional implications of a polymorphism in a primate-specific microRNA
Maria Lopez-Valenzuela*1, Oscar Ramírez1, Ignasi Torruella-Loran1, Antonio Rosas2, Samuel García-Vargas2, Marco de la Rasilla3, Carles Lalueza-Fox1, Yolanda Espinosa-Parrilla1
1Institut de Biologia Evolutiva (UPF-CSIC), Spain, 2Paleoanthropology Group, Department of Paleobiology, Museo Nacional de Ciencias Naturales (CSIC), Spain, 3Área de Prehistoria, Departamento de Historia, Universidad de Oviedo, Spain
P-2059 On the move: sex-biased migration during the Neolithic transition
Rita Rasteiro*1,2, Pierre-Antoine Bouttier1,3, Vítor C. Sousa1,4, Lounès Chikhi1,5
1Instituto Gulbenkian de Ciência, Portugal, 2Department of Genetics, University of Leicester, UK, 3Laboratoire Jean Kutzman, Université de Grenoble, France, 4Department of Genetics, Rutgers University, United States Minor Outlying Islands, 5CNRS, Université Paul Sabatier, ENFA, UMR 5174 EDB, France
P-2369 Rapid diversification of Drosophila telomere capping genes.
Raphaëlle Dubruille*1, Gabriel Marais2, Benjamin Loppin1
1CGphiMC - University of Lyon - CNRS, France, 2LBBE - University of Lyon - CNRS, France
P-2370 A genomic study of the contribution of DNA methylation to regulatory evolution in primates
Julien Roux*, Yoav Gilad
University of Chicago, USA
P-2288 Whole transcriptome sequencing to identify candidate genes in the response of the water flea, Daphnia magna, to infection with its parasite, Pasteuria ramosa.
Seanna McTaggart*1, Desiree Allen1, Timothee Cezard2, Carolyn Riddell1, Marian Thomson2, Urmi Trivedi2, Mark Blaxter1,2, Tom Little1
1University of Edinburgh, UK, 2The GenePool, UK, 3Center for Immunity, Infection and Evolution, UK
P-2060 Demographic inference and scans for selection in 28 sequenced gorillas
Jeffrey Kidd*1, Joanna Kelley2, Laurie Stevison3, August Woerner4, Laurel Johnstone4, Michael Hammer4, Jeff Wall3, Carlos Bustamante2, Great Apes Genome Diversity Consortium5
1University of Michigan, USA, 2Stanford University, USA, 3University of California, San Francisco, USA, 4University of Arizona, USA
P-2289 Estimating selection on codon usage in the face of noisy gene expression.
Edward Wallace*1,2, Edo Airoldi2, D. Allan Drummond1
1University of Chicago, USA, 2Harvard University, USA
P-2340 New tools for studying gene family evolution show changes in a single yeast species that correlate with the environment
Simon Lovell*, Simon Whelan, Ryan Ames, Daniel Money
University of Manchester, UK
P-2290 Determination of the mechanisms of regulatory divergence across a large collection of Saccharomyces cerevisiae strains
Brian Metzger*, Patricia Wittkopp
University of Michigan, USA
P-2247 Towards a Timeline in Networks of Lateral Gene Transfer during Prokaryote Evolution
Ovidiu Popa*, Giddy Landan, Tal Dagan
Institute of Molecular Evolution, Germany
P-2207 Nucleomorph genome sequence of the cryptophyte alga Chroomonas mesostigmatica reveals lineage-specific gene loss and genome complexity.
Christa Moore*, John Archibald
Dalhousie University, Canada
P-2061 How often does natural selection targets multiple, interacting genes? The prevalence of epistasis in recent human evolution
Natalia Petit*1, Arcadi Navarro1,4
1Institut de Biologia Evolutiva (CSIC-UPF), Spain, 2Departament de Ciències Experimentals i de la Salut (DCEXS).Universitat Pompeu Fabra, Spain, 3National Institute for Bioinformatics (INB), Population Genomics Node, Spain, 4Institució Catalana de Recerca i Estudis Avançats (ICREA), Spain
P-2167 Functional divergence and convergent evolution in the plastid-targeted glyceraldehyde-3-phosphate dehydrogenases of Archeasplastida and Chromalveolata. Gene duplication, endosymbiositic gene transfer, and two independent transitions to Calvin cycle function
Daniel Gaston*, Edward Susko, Andrew Roger
Dalhousie University, Canada
P-2062 Estimating selection coefficients in structured populations
Iain Mathieson*, Gil McVean
University of Oxford, UK
P-2063 Approximate Bayesian Computation Sheds Light on the Complex Demographic History of Orangutans (genus: Pongo)
Alexander Nater*, Maja Greminger, Natasha Arora, Carel van Schaik, Michael Krützen
Anthropological Institute and Museum, University of Zurich, Switzerland
P-2064 Selective processes affecting candidate genes in contrasting adaptive chromosomal inversions
Marta Pascual*, Pedro Simoes, Gemma Calabria, Cinta Pegueroles, Francesc Mestres, Joan Balanya
Universitat de Barcelona, Spain
P-2065 A new linkage disequilibrium based method for estimating effective population size
Lucie Gattepaille*, Mattias Jakobsson
Uppsala University, Sweden
P-2177 Sequence Features That Determine Transcriptional Enhancers
Jeffrey Chuang*1, Deborah Ritter1, Ningtao Shi1, Kourosh Zarringhalam1, Zhiqiang Dong2, Su Guo2
1Boston College, USA, 2University of California, USA
P-2208 Evolution of the 20-Gb genome of Norway Spruce (Picea abies)
Douglas Scofield*1, The Norway Spruce Genome Project1,2
1Umeå Plant Science Centre, Sweden, 2SciLifeLab, Sweden
P-2066 Estimating population sizes using the coalescent with recombination
Sara Sheehan*, Kelley Harris, Yun S. Song
UC Berkeley, USA
P-2067 Long-term evolution of quantitative traits in finite populations.
Harold P. de Vladar*, Nick Barton
IST Austria, Austria
P-2291 Modelling copper transcriptional reaction norm evolution in Saccharomyces cerevisiae
Andrea Hodgins-Davis*1, Aleksandra Adomas2, Daniel Rice3, Jeffrey Townsend1
1Yale University, USA, 2National Institute of Environmental Health Sciences, USA, 3Harvard University, USA
P-2068 Lizards and LINEs: Host Demography and Selection Affect the Fate of non-LTR Retrotransposons in the Anolis Genome
Marc Tollis*1,2, Stephane Boissinot1,2
1Queens College, City University of New York, USA, 2The Graduate Center, City University of New York, USA
P-2248 Large scale analysis of plasmids relationships through gene sharing networks and composition analyses
Manu Tamminen2, Emanuele Bosi1, Marko Virta2, Renato Fani1, Marco Fondi*1
1University of Florence, Italy, 2Department of Food and Environmental Sciences, Finland
P-2341 An evolutionary analysis of miRNA binding sites suggests an important role for genetic drift
Alfred Simkin*1, Fen-Biao Gao1, Jeffrey Jensen2,1
1University of Massachusetts Medical School, USA, 2Ecole polytechnique federale de Lausanne, Switzerland
P-2209 A global view of mutation patterns across eukaryotes.
Jean-François GOÛT*, Michael LYNCH
Lynch Lab, Indiana University, USA
P-2069 Assessing the evolutionary history of Theobroma cacao from resequenced genomes
Omar Cornejo*1, Keithanne Mockaitis2, Muh-Ching Yee1, Stefan Royaert3, Donald Livingstone III3, Ram Podicheti2, David Kuhn3, Carlos Bustamante1, Juan Carlos Motamayor3
1Stanford University, USA, 2Indiana University Center for Genomics and Bioinformatics, USA, 3USDA ARS SHRS, USA
P-2070 Elucidating the history of a rare spruce species endemic to Taiwan using Approximate Bayesian Computation
Sofia Bodare, Michael Stocks*, Martin Lascoux
Uppsala University, Sweden
P-2004 Sequencing of Pooled DNA Samples (Pool-Seq) Uncovers Complex Dynamics of Transposable Element Insertions in Drosophila melanogaster
Robert Kofler, Andrea Betancourt*, Christian Schlötterer
Institute for Population Genetics, Austria
P-2292 Gene expression patterns in two closely related crow taxa from a common garden RNA-seq experiment.
Jelmer Poelstra*1, Nagarjun Vijay1, Vittorio Baglione3, Inge Müller2, Martin Wikelski2, Jochen Wolf1
1Uppsala University, Sweden, 2Max Planck Institute for Ornithology, Germany, 3University of Valladolid , Spain, Spain
P-2168 The evolutionary history of the eukaryotic ribosome biogenesis pathway from a yeast perspective.
Ingo Ebersberger*1, Stefan Simm2, Enrico Schleiff2
1CIBIV MFPL, Austria, 2Institute for Molecular Biosciences, Goethe University, Germany
P-2071 Evolutionary and functional evidence for positive selection at the human CD5 immune receptor gene
Elena Carnero-Montoro*1, Lizette Bonet2, Johannes Engelken1,3, Mario Martínez-Florensa2, Francisco Lozano2,4, Elena Bosch1
1Institut de Biologia Evolutiva (UPF-CSIC), Spain, 2Institut d’Investigacions Biomèdiques August Pi i Sunyer, Centre Esther Koplowitz, Spain, 3Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Germany, 4Servei d’Immunologia, Hospital Clínic, Spain, 5Departament de Biologia Cel·lular, Immunologia i Neurociències, Facultat de Medicina, Universitat de Barcelona, Spain
P-2072 Dispersal processes underlying the recent pandemic caused by the plant pathogenic fungus Mycosphaerella fijiensis
Jean Carlier*1, Stéphanie Robert1, Adrien Rieux1, Fabien Halkett2, Marie-Françoise Zapater1, Luc De Lapeyre de bellaire1, François Bonnot1, Catherine Abadie1, Virginie Ravigné1
1CIRAD, UMR BGPI, France, 2INRA, UMR 1136, France, 3CIRAD, UPR 26, France
P-2293 Genetics of transcriptome-wide responses to ocean acidification in sea urchins
Daniel Runcie*1, David Garfield2, Narimane Dorey3, Sam Dupont3, Gregory Wray1
1Duke University, USA, 2EMBL, Germany, 3University of Gothenburg, Sweden
P-2260 Reconstructing functional networks of the last common ancestor
Aaron Goldman*, Laura Landweber
Princeton University, USA
P-2073 Climatic conditions during the Last Glacial Maximum affect the current genetic diversity of the European wild boar (Sus scrofa)
Sibelle Vilaca*1, Laura Iacolina2, Daniela Biosa2, Frank Zachos2, Marco Apollonio2, Massimo Scandura2, Giorgio Bertorelle1
1Università di Ferrara, Italy, 2Università di Sassari, Italy
P-2294 Comparative transcriptome analysis of increased encephalization in mormyrid  fishes
Olivier Fedrigo*1, William J. Nielsen1, Bruce A. Carlson2
1Duke University, USA, 2Washington University in St. Louis, USA
P-2342 Convergent evolution of concerted evolution in a master sex determiner
Eyal Privman*1, Sanne Nygaard2, Alexandra von Siebenthal1, Laurent Keller1, Yannick Wurm1,3
1University of Lausanne, Switzerland, 2University of Copenhagen, Denmark, 3Queen Mary, University of London, UK
P-2210 Large variations in the rate of DNA loss among vertebrates
Stephane Boissinot
Queens College, the City University of New York, USA
P-2074 The effect of recurrent partial sweeps on patterns of neutral diversity
Graham Coop*, Peter Ralph
Dept. of Evolution and Ecology, UC Davis, USA
P-2211 Influence of mating system on genome evolution in Caenorhabditis
Janna Fierst, John Willis, Timothy Ahearne, Rose Reynolds, Kristin Sikkink, William Cresko, Patrick Phillips*
University of Oregon, USA
P-2075 Genome-Wide Data Reveals the History and Structure of Mexican Populations
Christopher Gignoux*1, Andres Moreno2, Fouad Zakharia2, Juan Carlos Fernández López3, Simon Gravel2, Patricia Ortiz-Tello2, Eimear Kenny2, Karla Sandoval2, Martin Sikora2, Alejandra Contreras3, Victoria Robles3, Sandra Romero Hidalgo3, Rodrigo García Herrera3, Alessandra Carnevale3, Hector Rangel-Villalobos4, Victor Acuña-Alonzo5, Samuel Cañizales-Quinteros6, Irma Silva-Zolezzi3, Esteban González Burchard1, Carlos Bustamante2
1UCSF, USA, 2Stanford University, USA, 3National Institute of Genomic Medicine, Mexico, 4Universidad de Guadalajara, Mexico, 5Escuela Nacional de Antropología e Historia, Mexico, 6Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico
P-2249 The molecular basis of speciation in Drosophila.
Nitin Phadnis*, Harmit Malik
Fred Hutchinson Cancer Research Center, USA
P-2295 A transcriptomics view on speciation - gene expression studies in Ficedula flycatchers
Severin Uebbing*, Axel Künstner, Linnéa Smeds, Hannu Mäkinen, Páll Ólasson, Hans Ellegren
Institute for Ecology and Genetics, Uppsala University, Sweden
P-2076 The genomic basis of local adaptations in orangutans (Pongo spp.)
Maja P. Greminger*1, Kai N. Stölting2, Alexander Nater1, Maria Anisimova3,4, Giada Ferrari1, Heidi E. L. Lischer8, Remy Bruggmann5,6, Benoit Goossens7, Natasha Arora1, Carel P. van Schaik1, Michael Krützen1
1Anthropological Institute and Museum, University of Zurich, Switzerland, 2Unit of Ecology and Evolution, Department of Biology, University of Fribourg, Switzerland, 3Computational Biochemistry Research Group, Department of Computer Science, Swiss Federal Institute of Technology (ETH), Switzerland, 4Swiss Institute of Bioinformatics (SIB), Switzerland, 5Functional Genomics Center, University of Zurich, Switzerland, 6Department of Biology, University of Bern, Switzerland, 7School of Biosciences, Cardiff University, UK, 8Computational and Molecular Population Genetics Lab, Institute of Ecology and Evolution, University of Bern, Switzerland
P-2371 Integrating Functional and Population Genomics in Drosophila melanogaster
David Castellano*1,2, Antonio Barbadilla1,3
1Universitat Autónoma de Barcelona, Spain, 2Institut de Biotecnologia i Biomedicina, Spain, 3Departament de Genètica i Microbiologia, Spain
P-2378 Transgenerational epigenetic inheritance in Drosophila melanogaster
Jaime Grace*, Urban Friberg
Uppsala University, Sweden
P-2077 Chromosome-scale selective sweeps in Caenorhabditis elegans
Joshua Shapiro*1, Erik Andersen1, Justin Gerke1, Marie-Anne Félix Fèlix2, Leonid Kruglyak1,3
1Lewis-Sigler Institute for Integrative Genomics, Princeton University, USA, 2Institute of Biology of the Ecole Normale Superieure, France, 3Howard Hughes Medical Institute, Princeton University, Princeton, New Jersey, USA. 4 Department of Molecular Biology, Princeton University, USA
P-2078 Demographic inference using the transition matrix of allelic types from diploid genomic sequences
Yong Wang*, Kirk Lohmueller, Rasmus Nielsen
Department of Integrative Biology, University of California, Berkeley, USA
P-2079 Charting the footprint of natural selection through the genome of Drosophila melanogaster
Antonio Barbadilla*, David Castellano, Maite Barrón, Miquel Ràmia, Sònia Casillas
Institut de Biotecnologia i de Biomedicina - IBB / Department of Genetics and Microbiology, Campus Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain, Spain
P-2227 Identifying species trees from probabilities of clades or splits.
James Degnan*1,2, Elizabeth Allman3, John Rhodes3
1University of Canterbury, New Zealand, 2National Institute of Mathematical and Biological Synthesis, USA, 3University of Alaska Fairbanks, USA
P-2080 Population Genetics of the Sex-Locus in a closed Population of the Honey Bee (Apis mellifera) Marcel Medrano, Dr Michael Lattorff, Pr Dr Robin Moritz
Marcel Medrano*, Michael Lattorff, Robin Moritz
Martin-Luther-Universität Halle-Wittenberg, Germany
P-2081 Aging and the loss of immune repertoire genetic diversity
Philip Johnson*1, Andrew Yates2, Jorg Goronzy3, Rustom Antia1
1Emory University, USA, 2Albert Einstein College of Medicine, USA, 3Stanford School of Medicine, USA
P-2296 The Evolution of Reproductive Complexity in Male-Pregnant Fishes
Tony Wilson*1, Marie Gauthier1, Kai Stoelting1,2, Camilla Whittington1
1University of Zurich, Switzerland, 2University of Fribourg, Switzerland
P-2343 Evolution and Diversification of Small Heat Shock Protein in Plants
Elizabeth Waters*, Bharath Bharadwaj
San Diego State University, USA
P-2178 Modeling expression evolution with varying mutational effect sizes
Rori Rohlfs*1, Patrick Harrigan3, Rasmus Nielsen1,2
1University of California, Berkeley, USA, 2University of Copenhagen, Denmark, 3University of California, San Francisco, USA
P-2082 Exploring genetic interaction as a predictor for non-random association among loci
Ching-Hua Shih*1, Shuwei Li1, Hyun Jung Park2, Luay Nakhleh1,2, Michael Kohn1
1Department of Ecology and Evolutionary Biology, Rice University, USA, 2Department of Computer Science, Rice University, USA
P-2169 Understanding the exceptional amplification of the STS gene family involved in resveratrol synthesis in grapevine
Claire Parage1, Raquel Tavares*2, Stéphane Réty4, Raymonde Baltenweck1, Anne Poutaraud1, Dimitri Heintz5, Raphaël Lugan5, Gabriel Marais2, Sébastian Aubourg3, Philippe Hugueney1
1University f Strasbourg / INRA, France, 2University of Lyon1 / CNRS, France, 3INRA, France, 4CNRS, France, 5CNRS, France
P-2083 Human evolutionary processes and genetic variation as revealed by mtDNA simulations
Aida Miró-Herrans*, Connie Mulligan
University of Florida, USA
P-2084 Sex ratio between Y/A chromosomes, Y-haplotype diversity and frequency spectrum patterns confirms a marked ancient isolation in pigs (Sus scrofa)
Oscar Ramirez1, Ana Ojeda2, Marcel Amills2,3, Greger Larson4, Miguel Pérez-Enciso2,3, Sebastian Ramos-Onsins*3
1Institute of Evolutionary Biology (UPF-CSIC), Spain, 2Departament de Ciència Animal i dels Aliments Facultat de Veterinaria. Universitat Autònoma de Barcelona (UAB), Spain, 3Department of Animal Genetics Centre for Research in Agricultural Genomics (CRAG) Consortium CSIC-IRTA-UAB-UB Edifici CRAG, Campus UAB, Spain, 4Department of Archaeology, University of Durham, UK, 5Institut Català de Recerca i Estudis Avançats (ICREA), Spain
P-2085 Depth-related changes in coral zooxanthellae
Nikolaos Schizas*1, Matthew Lucas1, Matthew Smith1,2, Ernesto Weil1
1University of Puerto Rico, USA, 2University of Wisconsin - Milwaukee, USA
P-2179 Placental endogenous retroviruses facilitate rapid evolution of core trophoblast regulatory network.
Edward Chuong*1, Mohammad Rumi2, Michael Soares2, Julie Baker1
1Stanford University, USA, 2University of Kansas Medical Center, USA
P-2212 Genomic response to drastic environmental change
Thomas Cuypers*, Paulien Hogeweg
Utrecht University, The Netherlands
P-2228 Green and red algal phylogenetic signals in nuclear genes shared by eukaryotes bearing secondary plastids of green algal origin: looking beyond endosymbiotic versus lateral gene transfer
Shinichiro Maruyama*, John Archibald
Dalhousie University, Canada
P-2372 Epigenetic inheritance versus mobility in fluctuating environments
Luca Ferretti*1, Michele Cortelezzi2
1CRAG, Spain, 2Universita' di Pisa, Italy
P-2146 Robustness to stress in antibiotic resistant Escherichia coli
Ana Sousa*, Sandra Trindade, Isabel Gordo
Instituto Gulbenkian de Ciencia, Portugal
P-2086 The joint allele frequency spectrum of multiple populations: A coalescent theory approach
Hua Chen
Department of Epidemiology and Biostatistics, Harvard School of Public Health, USA
P-2344 The details in the Devils: horizontal transfer of transposable elements in a carnivorous marsupial
Sarah Schaack
Reed College, USA
P-2087 Latitudinal clinal variation in a blue-absorbing visual pigment of butterflies
Furong Yuan, Adriana Briscoe*
University of California, Irvine, USA
P-2088 Coalescent analysis of archaic hominin data
Swapan Mallick*, David Reich
Harvard Medical School, USA
P-2213 Comparative proteomic characterization of protein disorder distribution across Eukaryota
Catherine Mooney*, Denis C. Shields, Therese A. Holton
UCD, Ireland
P-2147 Melanesian Blond Hair is Caused by an Amino Acid Change in TYRP1
Eimear Kenny*1, Nicholas Timpson2, Martin Sikora1, Muh-Ching Yee1, Andres Moreno Estrada1, Celeste Eng3, Scott Huntsmann3, Esteban Gonzalez Burchard3, Mark Stoneking4, Carlos Bustamante1, Sean Myles1
1Stanford University, USA, 2University of Bristol, UK, 3University of California San Francisco, USA, 4Max Planck Institute for Evolutionary Anthropology, Germany
P-2089 Using deterministic functions to derive approximate coalescent distributions
Ethan Jewett*, Noah Rosenberg
Stanford University, USA
P-2148 Phenotypic plasticity of body size in Daphnia pulex
France Dufresne
Université du Québec à Rimouski, Canada
P-2180 Personal and population genomics of human regulatory variation
Benjamin Vernot*, Andrew Stergachis, John Stamatoyannopoulos, Joshua Akey
Department of Genome Sciences, University of Washington, USA
P-2090 Parallel evolution in Drosophila species along a latitudinal cline
Heather Machado*1, Alan Bergland1, Paul Schmidt2, Dmitri Petrov1
1Stanford University, USA, 2University of Pennsylvania, USA
P-2297 Cryptic genetic variation underlying stress resistance in evolved lines of Caenorhabditis remanei
Kristin Sikkink*, Catherine Ituarte, Rose Reynolds, Patrick Phillips, William Cresko
University of Oregon, USA
P-2181 Adaptive cis-regulatory evolution of age-related differentially expressed genes in the human brain
Michael McGowen*1, Kirstin Sterner2, Jennifer Baker3, Chet Sherwood3, Christopher Kuzawa4, Harry Chugani1, Leonard Lipovich1, Lawrence Grossman1, Derek Wildman1
1Wayne State University School of Medicine, USA, 2University of Oregon, USA, 3The George Washington University, USA, 4Northwestern University, USA
P-2091 A Simple Method for Finding Explicit Solutions to the Dynamics of Diffusion Processes with General Diploid Selection
Yun Song1,2, Matthias Steinruecken*1
1UC Berkeley, Department of Statistics, USA, 2UC Berkeley, Computer Science Division, USA
P-2092 Formation of reproductive barriers in a hybrid zone of American and Caribbean Drosophila melanogaster
Joyce Kao*, Sergey Nuzhdin
University of Southern California, USA
P-2298 Comparative Transcriptomics for Eye Diversification of Cephalopod: Evolution of Camera eye and Pinhole eye
Atsushi Ogura
Ochanomizu University, Japan
P-2373 The role of epigenetics in the evolution of sexual attraction in moths
Astrid T. Groot
University of Amsterdam, The Netherlands
P-2345 Frequent subcellular relocalization after gene duplication during the evolution of the Brassicaceae family
Shao-Lun Liu, Angel Pan, Keith Adams*
University of British Columbia, Canada
P-2250 Sequence similarity networks reveal gene fusion evolution.
Pierre-Alain Jachiet*1, Romain Pogorelcnik1, Eric Bapteste1, Philippe Lopez1
1Université Pierre et Marie Curie, France, 2LIMOS UMR CNRS 6158, France
P-2093 Genetic evidence of two major prehistoric migrations of modern humans into the Tibetan plateau
Xuebin Qi1, Chaoying Cui2, Yi Peng1,5, Xiaoming Zhang1,5, Zhaohui Yang1,5, Hui Zhang1, Kun Xiang1,5, xiangyu Cao1,5, Yi Wang1,5, Ouzhuluobu .2, Basang .3, Ciwangsangbu .3, Bianba .2, Gonggalanzi .2, Tianyi Wu4, Hua Chen6, Hong Shi1, Bing Su*1
1State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, China, 2School of Medicine, Tibetan University, China, 3People’s Hospital of Dangxiong County, China, 4National Key Laboratory of High Altitude Medicine, High Altitude Medical Research Institute, China, 5Graduate School of Chinese Academy Sciences, China, 6Department of Epidemiology, Harvard School of Public Health, USA
P-2299 Divergent gene expression patterns produce highly similar aggressive phenotypes in male and female cichlid fish (Julidochromis)
Suzy Renn
Reed College, USA
P-2300 Evidence for positive selection on a number of  microRNA regulatory interactions during recent human evolution including regulation of a pigmentation gene
Jingjing Li1, Yu Liu1, Xiaofeng Xin1, TaeHyung Kim1, Eduardo Aguiar Cabeza1, Jie Ren1, Rasmus Nielsen1,2, Jeffrey Wrana1, Zhaolei Zhang*1
1University of Toronto, Canada, 2UC Berkeley, USA
P-2301 Large-Scale Transcriptome Sequencing and Gene Analyses in the Crab-Eating Macaque (Macaca fascicularis) for Biomedical Research
Young-Hyun Kim*1,2, Sang-Je Park1,3, Jae-Won Huh1, Kyu-Tae Chang1,2
1National Primate Research Center, Korea Research Institute of Bioscience and Biotechnology, Republic of Korea, 2University of Science & Technology, National Primate Research Center, KRIBB, Republic of Korea, 3Department of Biological Sciences, College of Natural Sciences, Pusan National University, Republic of Korea
P-2302 Identification and characterization of rhesus monkey genes from placenta full-length cDNA libraries: comparative analysis with human genes
Sang-Je Park*1,2, Young-Hyun Kim1,3, Jae-Won Huh1, Sang-Rae Lee1, Kyu-Tae Chang1,3
1National Primate Research Center, Korea Research Institute of Bioscience and Biotechnology, Republic of Korea, 2Department of Biological Sciences, College of Natural Sciences, Pusan National University, Republic of Korea, 3University of Science & Technology, National Primate Research Center, KRIBB, Republic of Korea
P-2303 Bioinformatic Analysis and Experimental Validation of Fusion Gene in Human, Rhesus Monkey, and Crab-Eating Monkey
Jae-Won Huh*1, Sang-Je Park1,2, Young-Hyun Kim1,3, Kyu-Tae Chang1,3, Sang-Rae Lee1
1National Primate Research Center, Korea Research Institute of Bioscience and Biotechnology, Republic of Korea, 2Department of Biological Sciences, College of Natural Sciences, Pusan National University, Republic of Korea, 3University of Science & Technology, National Primate Research Center, KRIBB, Republic of Korea
P-2094 Adaptive evolution of loci covarying with the human African Pygmy Phenotype
Isabel Mendizabal*1, Urko M. Marigorta1, Oscar Lao0,2, David Comas1
1Institut de Biologia Evolutiva (CSIC-UPF), Spain, 2Department of Forensic Molecular Biology, Erasmus University Medical Center, The Netherlands
P-2229 Recombinations associated with Gene Transfer Events Reveal a Complex Evolutionary History of Aminoacyl-tRNA Synthetases
Greg Fournier1,2
1MIT, USA, 2NASA Astrobiology Institute, USA
P-2149 Genotyping Candidate Loci for Colorectal Cancer: A Pointer to Ancestral Susceptibility.
Stefanie Huhn*1, Melanie Bevier1, Barbara Pardini2, Alessio Naccarati2, Ludmila Vodickova2,3, Jan Novotny4, Pavel Vodicka2,3, Kari Hemminki1,5, Asta Försti1,5
1Department of Molecular Genetic Epidemiology, German Cancer Research Center Heidelberg, Germany, 2Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Czech Republic, 3Institute of Biology and Medical Genetics, 1st Faculty of Medicine, Charles University, Czech Republic, 4Department of Oncology, General Teaching Hospital, U Nemocnice 2, Czech Republic, 5Center of Primary Health Care Research at the Clinical Research Center, Lund University, Sweden
P-2095 Rapid fixation of duplications and deletions in experimental Caenorhabditis elegans populations during adaptive recovery.
Vaishali Katju*, James Farslow, Ulfar Bergthorsson
University of New Mexico, USA
P-2096 Coalescent-based Species Tree Inference from Gene Tree Topologies Under Incomplete Lineage Sorting by Maximum Likelihood
Yufeng Wu
University of Connecticut, USA
P-2304 Age-related LincRNAs in human brain
Zhisong He*1, Haiyang Hu1, Philipp Khaitovich1,2
1CAS-MPG Partner Institute for Computational Biology, China, 2Max Planck Institute for Evolutionary Anthropology, Germany
P-2346 Phylogeny and Nomenclature of Histone Variants
Paul B. Talbert*1, Kami Ahamd2, Geneviève Almouzni3, Juan Ausio4, Frederic Berger5, Prem L. Bhalla6, William M. Bonner7, W. Zacheus Cande8, Brian P. Chadwick9, Simon W. L. Chan10, George A. M. Cross11, Liwang Cui12, Stefan I. Dimitrov13, Detlef Doenecke14, José M. Eirin-López15, Martin A. Gorovsky16, Sandra B. Hake17, Barbara A. Hamkalo18, Sarah Holec5, Steven E. Jacobsen19
1Howard Hughes Medical Institute, Fred Hutchinson Cancer Research Center, USA, 2Department of BCMP, Harvard Medical School, USA, 3CNRS, Institut Curie, Centre de Recherche, France, 4University of Victoria, Canada, 5Temasek Lifesciences Laboratory, National University of Singapore, Singapore, 6Plant Molecular Biology and Biotechnology Group, The University of Melbourne, Australia, 7Laboratory of Molecular Pharmacology, CCR, NCI, NIH,, USA, 8Department of Molecular and Cell Biology, University of California, USA, 9Department of Biological Science, Florida State University, USA, 10Department of Plant Biology, UC Davis / HHMI, USA, 11Laboratory of Molecular Parasitology, The Rockefeller University, USA, 12Department of Entomology, Pennsylvania State University, USA, 13Laboratoire de Biologie Moléculaire et Cellulaire de la Différenciation, Institut Albert Bonniot, France, 14Department of Biochemistry, University of Goettingen, Germany, 15Department of Cellular and Molecular Biology, University of A Coruna, Spain, 16Department of Biology, University of Rochester, USA, 17Center for Integrated Protein Science Munich at the Adolf-Butenandt Institute, Department for Molecular Biology, Ludwig-Maximilians-University Munich, Germany, 18Department of Molecular Biology & Biochemistry, University of CA, USA, 19Howard Hughes Medical Institute, Department of Molecular Cellular and Developmental Biology, University of California, Los Angeles,, USA
P-2347 140 million years of multigene family evolution: Origin and recombination history of the avian MHC class IIB
Reto Burri*1,2, Marta Promerová3, Luca Fumagalli2
1Department of Ecology & Genetics, Uppsala University, Sweden, 2Department of Ecology & Evolution, University of Lausanne, Switzerland, 3Institute of Vertebrate Biology, AS CR, Czech Republic
P-2348 Determining the evolutionary history of gene families
Ryan Ames*1, Daniel Money2, Vikramsinh Ghatge1, Simon Whelan1, Simon Lovell1
1University of Manchester, UK, 2University of Kansas, USA
P-2214 Testing the “suppressed recombination” model of chromosomal evolution during human-chimpanzee speciation.
Marta Farré1, Aurora Ruiz-Herrera*1,2
1Departament de Biologia Cel•lular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona, Spain, 2Institut de Biotecnologia i Biomedicina (IBB), Universitat Autònoma de Barcelona, Spain
P-2305 Positively charged residues affect the speed of translation much more than non-optimal codons
Catherine Charneski*, Laurence Hurst
University of Bath, UK
P-2215 High variation of mitochondrial gene order in basidiomycetes
Gabriela Aguileta*1, Elsa Petit2, Tatiana Giraud3, Toni Gabaldon1, Michael Hood2
1Centre for Genomic Regulation (CRG), Spain, 2Department of Biology, Amherst College, USA, 3Ecologie, Systematique et Evolution, Universite Paris Sud, France
P-2150 Evolutionary origin and process, and genetic diversity of goldfish
Tomoyoshi Komiyama, Atsushi Ogura, Kazuho Ikeo, Takashi Gojobori*
National Institute of Genetics, Japan
P-2097 Recurrent positive selection at the same amino acids in primates and human populations
Renee George*1, Graham McVicker2, Josh Akey1, Willie Swanson1
1University of Washington, USA, 2University of Chicago, USA
P-2098 Phylogeography in habitat generalists and specialists in the granite inselbergs of Namibia.
Sara Tromp, Anne Goldizen, Jenny Seddon*
The University of Queensland, Australia
P-2216 Structural evolution of primate genomes mediated by highly similar duplicated sequences undergoing gene conversion
Jeffrey Fawcett*, Hideki Innan
Graduate University of Advanced Studies, Japan
P-2306 Adaptive evolution of Pseudomonas aeruginosa revealed by archetypal analysis of gene expression data
Juliane Thoegersen*, Lars Jelsbak, Soeren Molin
Technical University of Denmark, Denmark
P-2357 Evolution of the Kelch domain-containing family of protein phosphatases from plants and alveolate protists
Claudio Slamovits*1, Santiago Mora-García2
1Dalhousie University, Dept. of Biochemistry and Molecular Biology, Canada, 2Instituto de Investigaciones Bioquímicas "Luis F. Leloir", Argentina
P-2170 Evolution of BCL-2 homologous proteins: a trip to Indels
CNRS LBMC UMR5239, France
P-2374 Intron positional conservation: a new paradigm of evolutionary conservation
Michal Chorev, Liran Carmel*
The Hebrew University of Jerusalem, Israel
P-2349 Biological meaning of pseudogenization in human evolution
Yoko Satta
The Graduate University for Advanced Studies (Sokendai), Japan
P-2251 An initial survey of the protein-protein interaction network of the plant pathogen Phytophthora infestans and its dynamics during infection
Michael F Seidl*, Adrian Schneider, Berend Snel
University Utrecht, The Netherlands
P-2252 Evidence for Network Evolution in an Arabidopsis Interactome Map
Benoit Charloteaux*1,2, Anne-Ruxandra Carvunis2,3, Matija Dreze2,3, Samuel J. Pevzner2,3, Murat Tassan2,5, Mary Galli6, Sabrina Rabello1,7, Gourab Ghoshal1,7, Jean Vandenhaute4, Michel Georges1, Joseph R. Ecker6, Michael E. Cusick2,3, David E. Hill2,3, Frederick P. Roth1,5, Albert-Laszlo Barabasi1,7, Pascal Braun2,3, Marc Vidal2,3
1Unit of Animal Genomics, GIGA-R and Faculty of Veterinary Medicine, University of Liège, Belgium, 2Center for Cancer Systems Biology, Dana-Farber Cancer Institute, USA, 3Department of Genetics, Harvard Medical School, USA, 4Unité de Recherche en Biologie Moléculaire, Facultés Universitaires Notre-Dame de la Paix, Belgium, 5Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, USA, 6Genomic Analysis Laboratory and Plant Biology Laboratory, The Salk Institute for Biological Studies, USA, 7Center for Complex Network Research, Northeastern University, USA
P-2099 Genetics of malaria susceptibility across three African populations: Kenya, Malawi and Gambia.
Chris Spencer
Wellcome Trust Centre for Human Genetics, UK
P-2100 Understanding genetic adaptations to varying dietary selenium intakes in human populations
Louise C White*, Genís Parra, Sergi Castellano
Max Planck Institute for Evolutionary Anthropology, Germany
P-2217 Abundance of ultramicro inversions within whole genome alignments between closely related species
Yuichiro Hara*, Tadashi Imanishi
National Institute of Advanced Industrial Science and Technology, Japan
P-2101 Establishment of new mutations in changing environments
Stephan Peischl*1,2, Mark Kirkpatrick2
1University of Bern, Switzerland, 2University of Texas at Austin, USA
Samuel Loftus, Douglas Crawford*
University of Miami, USA
P-2102 Molecular Evolution of DNA Sequences on Neo-X and Neo-Y Chromosomes in Drosophila albomicans.
Kazuhiro Satomura*, Koichiro Tamura
Tokyo Metropolitan University, Japan
P-2218 Structural evolution in high-grade serous ovarian cancer and its influence on patient outcome and chemotherapy resistance
Roland Schwarz*1,2, Susanna Cooke3, Charlotte Ng1,2, Jill Temple1, James Brenton1,2, Florian Markowetz1,2
1Cancer Research UK Cambridge Research Institute, UK, 2Department of Oncology, University of Cambridge, UK, 3The Wellcome Trust Sanger Institute, UK
P-2350 Gene conversion as both a boost and drag on diversity in a gene family across genetically divergent populations of the copepod Tigriopus californicus
Christopher Willett
University of North Carolina, USA
P-2151 Can the evolutionary dynamics of structural disorder contribute to biological divergence and neostructuralization?
Madolyn MacDonald2, Juan Felipe Ortiz Quinonez1, Patrick Masterson1, Jessica Siltberg-Liberles*1
1University of Wyoming, USA, 2Rochester Institute of Technology, USA
P-2253 Hierarchical modularity and the evolution of genetic interactomes across species
Colm Ryan*1,2, Assen Roguev1, Kristin Patrick1, Jiewei Xu1, Harlizawati Jahari1, Nevan J. Krogan1
1University of California, San Francisco, USA, 2University College Dublin, Ireland
P-2103 Dynamic transmission, host quality and population structure in a multi-host parasite of bumble bees
Mario X. Ruiz-González*1,2, John Bryden3, Yannick Moret4, Christine Reber-Funk5, Paul Schmid-Hempel5, Mark J. F. Brown1,3
1Department of Zoology, School of Natural Sciences, Trinity College Dublin, Ireland, 2Instituto de Biología Molecular y Celular de Plantas, C.S.I.C. – U.P.V., Spain, 3School of Biological Sciences, Royal Holloway, University of London, UK, 4Université de Bourgogne, UMR CNRS, France, 5ETH Zurich, Institute of Integrative Biology (IBZ), Switzerland
P-2182 A coherent theory of ultraconserved non-coding element evolution
Philipp Bucher1,2
1EPFL, Switzerland, 2Swiss Institute of Bioinformatics, Switzerland
P-2254 Genomes of saprophytic Thraustotheca clavata and parasitic Achlya hypogyna shed light on the pathogenicity of oomycetes
Ian Misner*1, Cedric Bicep3, Eric Bapteste3, Sebastien Halary4, Philippe Lopez3, J Craig Bailey2, Christopher Lane1
1University of Rhode Island, USA, 2University of North Carolina at Wilmington, USA, 3Universite Pierre et Marie Curie, France, 4Universite de Montreal, Canada
P-2255 Epistatis and the order of mutations in real and model fitness landscapes
Guillaume Achaz*1, Dan Weinreich2, Yutaka Kobayashi3, Atsushi Yamauchi4, Fumio Tajima0
1Univerité Pierre et Marie Curie, France, 2Brown University, USA, 3Tokyo University, Japan, 4Kyoto University, Japan
P-2256 Evolution of novel traits in the plant metabolic network through gene and genome duplication
Michaël Bekaert4, Corey Hudson1, Patrick Edger2, Emily Puckett2, Chris Pires2,1, Gavin Conant*1,3
1Informatics Institute, University of Missouri, USA, 2Division of Biological Sciences, University of Missouri, USA, 3Division of Animal Sciences, University of Missouri, USA, 4Institute of Aquaculture, University of Stirling, UK
P-2308 Mitochondrial genotypes alter the nuclear transcriptional response to varied levels of hypoxia in Drosophila: Mito-Nuclear Epistasis meets Systems Genetics
David Rand*, Patrick Flight, Nick Jourjine, Lei Zhu
Brown University, USA
P-2104 The demographic and adaptive history of domesticated and wild yeast
Angela Bean*1, Nicholas Renzette1, Oliver Rando1, Jeffrey Jensen1
1University of Massachusetts Medical School, USA, 2EPFL, Switzerland
P-2219 Horizontal gene transfer and gene conversion as a novel mechanism of intron loss
Nancy Hepburn, Derek Schmidt, Jeff Mower*
University of Nebraska-Lincoln, USA
P-2309 The evolution of gene expression in numerous cancer lines
Corey M. Hudson*1, Michaël Bekaert0,2, Gavin C. Conant1
1University of Missouri, USA, 2University of Stirling, UK
P-2105 A Hidden Markov Model for inferring natural selection and other demographic parameters from allele frequency data
Anand Bhaskar*1, Yun Song1,2, Matthias Steinruecken2
1Computer Science Division, University of California, Berkeley, USA, 2Department of Statistics, University of California, Berkeley, USA
P-2152 Genome-wide genetic architecture of morphological traits in yeast
Wei-Chin Ho*, Jianzhi Zhang
University of Michigan, USA
P-2106 Genomics of Oil Exposure
Marjorie Oleksiak*, Douglas Crawford
University of Miami, USA
P-2310 Exploring the roles of molecular evolution, expression patterns and function of posterior HoxA and HoxD genes in teleost paired-fin diversity: novel observations from non-model taxa.
Sophie Archambeault*, Karen Crow-Sanchez
San Francisco State University, USA
P-2107 Demographic processes or mitochondrial selective sweep in shaping patterns of genetic diversity in a Neotropical treefrog endemic from the Brazilian Atlantic forest
Tuliana Oliveira Brunes*1,2, João Paulo Soares de Cortes2, João Alexandrino3, Célio Fernando Baptista Haddad2, Fernando Sequeira1
1CIBIO-UP/PT, Portugal, 2UNESP, Brazil, 3UNIFESP, Brazil
P-2364 SuiteMSA and improving MSAs
Catherine Anderson, Etsuko Moriyama*
University of Nebraska-Lincoln, USA
Ravi Subramanian*, John Coffin
Tufts University, USA
P-2257 Dynamics and adaptive benefits of emergence and modular rearrangements of protein domains
Erich Bornberg-Bauer
Insitute for Evolution and Biodiversity, Germany
Sandra Beleza*1,2, Nick Jonhson1, Sophie Candille1, Isabel Inês Araújo3, António Correia e Silva3, Mark Shriver4, Jorge Rocha5,6, Greg Barsh1,7, Hua Tang1
1Genetics Department, Stanford University, USA, 2Instituto de Patologia e Imunologia Molecular da Universidade do Porto (IPATIMUP), Portugal, 3Universidade de Cabo Verde (UNI-CV), Cape Verde, 4Department of Anthropology, Penn State University, USA, 5Centro de Investigação em Biodiversidade e Recursos Genéticos (CIBIO), Portugal, 6Departamento de Zoologia e Antropologia, Faculdade de Ciências, Universidade do Porto, Portugal, 7HudsonAlpha Institute for Biotecnhology, USA
P-2154 Difference in Gene expression between dry and wet thalli of lichen Usnea bismolliuscula
Mieko Kono*1, Yoshihito Ohmura2, Yoko Satta1
1Department of Evolutionary Studies of Biosystems, the Graduate University for Advanced Studies [SOKENDAI], Japan, 2Department of Botany, National Museum of Nature and Science, Japan
P-2155 Revaluating duplication gene evolution from the perspective of their phylogenetic origin
Krishna Swamy*1,2, Chien-Hao Su2, Daryi Wang3, Huai-Kuang Tsai1,2
1Bioinformatics Program, Taiwan International Graduate Program,Academia Sinica, Taiwan, 2Institute of Information Science, Academia Sinica, Taiwan, 3Biodiversity Research Center, Academia Sinica, Taiwan
P-2258 Network-level and population genetics analysis of the insulin/TOR signal transduction pathway across human populations.
Hafid Laayouni*1, Pierre Luisi1, David Alvarez-Ponce2, Martin Sikora3, Jaume Bertranpetit1
1Inuversitat Pompeu Fabra, Spain, 2National University of Ireland Maynooth, Ireland, 3Stanford University School of Medicine, USA
P-2375 Promoter regions of duplicated Schistosoma mansoni genes crucial for infection success undergo rapid epigenetic modifications in varying environments while remaining genetically stable
Cecile Perrin1, Julie MJ Lepesant1, Emmanuel Roger2, David Duval1, Virginie Thuillier1, Jean Francois Alliene1, Guillaume Mitta1, Christoph Grunau1, Celine Cosseau*1
1UMR5244 CNRS UPVD, France, 2CNRS UMR 8204, France
P-2183 A Mammalian Conserved Element Derived from SINE Displays Enhancer Properties Recapitulating Satb2 Expression in Early-Born Callosal Projection Neurons
Hidenori Nishihara*1, Anne Teissier2, Naoki Kobayashi1, Kensuke Tashiro1, Akiko Nakanishi1, Takeshi Sasaki3, Masaki Iwakiri1, Kazuki Izawa1, Kuo Yan4, Victor Tarabykin4, Kenta Sumiyama5, Mika Hirakawa6, Alessandra Pierani2, Norihiro Okada1
1Tokyo Institute of Technology, Japan, 2Université Paris Diderot, France, 3Tokyo University of Agriculture, Japan, 4Max Planck Institute for Experimental Medicine, Germany, 5National Institute of Genetics, Japan, 6JT Biohistory Research Hall, Japan
P-2184 SINE-derived element as a regional determinant for the hypothalamic specificity of mammalian diencephalic Fgf8 enhancer
Akiko Nakanishi*1, Naoki Kobayashi1, Asuka Hirano-Suzuki2, Hidenori Nishihara1, Takeshi Sasaki1,5, Mika Hirakawa3,6, Kenta Sumiyama4, Tomomi Shimogori2, Norihiro Okada1
1Graduate School of Biotechnology, Tokyo Institute of Technology, Japan, 2RIKEN Brain Science Institute, Japan, 3Bioinformatics Center, Institute for Chemical Research, Kyoto University, Japan, 4National Institute of Genetics, Japan, 5Department of Human and Animal-Plant Relationships, Faculty of Agriculture, Tokyo University of Agriculture, Japan, 6Science Communication and Pruduction, JT Biohistory Research Hall, Japan
P-2108 Kernel Approximate Bayesian Computation
Shigeki Nakagome*, Kenji Fukumizu, Shuhei Mano
The Institute oif Statistical Mathematics, Japan
P-2109 Patterns of genetic diversity and population structure in domestic rabbits: early steps of domestication and the subsequent process of breed formation
Joel Alves*1,2, Miguel Carneiro1,2, Sandra Afonso1, Susana Lopes1, Hervé Garreau3, Samuel Boucher4, Daniel Allain3, Guillaume Queney5, Pedro Esteves1,6, Gerard Bolet3, Nuno Ferrand1,2
1CIBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Portugal, 2Departamento de Biologia, Faculdade de Ciências, Universidade do Porto, Portugal, 3INRA, Institut National de la Recherche Agronomique, France, 4Labovet Conseil, France, 5ANTAGENE, Wildlife Genetics Laboratory, France, 6CITS, Centro de Investigação em Tecnologias da Saúde, IPSN, CESPU, Portugal
P-2311 Gene expression analysis in neural tissues of the Chordate, Ciona intestinalis by the use of a customized microarray
Hiromi Matsumae*1, Mayuko Hamada2, Manabu Fujie2, Hiroshi Tanaka1, Yoshihito Niimura1, Takeshi Kawashima2
1Department of Bioinformatics, Tokyo Medical and Dental University, Japan, 2Marine Genomics Unit and Genome Sequencing Center, Okinawa Institute of Science and Technology Graduate University, Japan
P-2156 Investigating Two Different Mechanisms of Multiple-Host Recognition in the Bacterial Transferrin Receptor
Anastassia Pogoutse*1, Charles Calmettes1, Rong-hua Yu2, Estela Costa2, Anthony Schryvers2, Trevor Moraes1
1University of Toronto, Canada, 2University of Calgary, Canada
P-2376 DNA methylation in Biomphalaria glabrata the intermediate host of the human parasite Schistosoma mansoni: role of epigenetics in the coevolution of host / parasite interactions.
Sara Fneich*1,2, Julie Lepesant1,2, Céline Cosseau1,2, Michael Reichelt3, Christoph Grunau1,2
1Université de Perpignan Via Domitia, France, 2CNRS, UMR 5244, Ecologie et Evolution des Interactions (2EI), France, 3Max-Planck-Institut fuer Chemische Oekologie, Germany
P-2312 Characterizing Gene Expression Variation Across Seven Diverse Human Populations
Alicia Martin*1, Helio Costa1, Jeffrey Kidd2, Brenna Henn1, Muh-Ching Yee1, Stephen Montgomery1, Howard Cann3, Michael Snyder1, Carlos Bustamante1
1Stanford University School of Medicine, Department of Genetics, USA, 2University of Michigan School of Medicine, Department of Human Genetics, USA, 3Foundation Jean Dausset, Centre d'Etude du Polymorphisme Humain, France
P-2157 Phenol metabolisms in yeasts: identification and evolutionary analysis of genes involved in gentisate and 3-oxoapidate pathways in Candida parapsilosis
Leszek Pryszcz*1, Josef Nosek2, Toni Gabaldón1
1Department of Bioinformatics and Genomics, CRG-Centre for Genomic Regulation, Spain, 2Department of Biochemistry, Faculty of Natural Sciences, Comenius University, Slovakia
P-2171 MetaPhOrs: orthology and paralogy predictions from multiple phylogenetic evidence using a consistency-based confidence score.
Leszek Pryszcz*, Jaime Huerta-Cepas, Toni Gabaldón
CRG-Centre for Genomic Regulation, Spain
P-2351 Evolution of olfactory and gustatory receptor repertoires in Drosophila.
Eri Kudo, Mao Nakamura, Atsushi Ogura, Rumi Kondo*
Ochanomizu University, Japan
P-2110 Inferring natural selection by stratifying a single genome sequence
Naoki Osada
National Institute of Genetics, Japan
P-2111 Combinatorial properties of coalescent trees and relatives
Filippo Disanto, Thomas Wiehe*
Universitaet zu Koeln, Germany
P-2112 Correcting principal components of spatial population genetic variation under isolation by distance models
Eric Frichot*1, Sean Schoville1, Guillaume Bouchard0,2, Olivier François1
1Université Joseph Fourier, CNRS, TIMC-IMAG UMR 5525, France, 2Xerox Research Center Europe, France
P-2313 Stress and polyphenism: an RNA-Seq analysis in the butterfly Bicyclus anyana
Christopher Wheat1,2
1University of Helsinki, Finland, 2Stockholm University, Sweden, 3Leiden University, The Netherlands, 4University of California, Irvine, USA
P-2113 Climate adaptation of flowering time in the Mediterranean model species Medicago truncatula
Concetta Burgarella*1, Nathalie Chantret1, J. Marie Prosperi1, Stephane De Mita2, Peter Tiffin3, Joelle Ronfort1
1INRA, France, 2INRA, France, 3Univ. of Minnesota, USA
P-2352 Contrasted patterns of selective pressures in three recent paralogous gene pairs in the Medicago genus (L.)
Joan Ho-Huu1,2, Joëlle Ronfort1, Stéphane De Mita3,5, Thomas Bataillon4, Jean-Marie Prosperi1, Nathalie Chantret*1
1INRA, France, 2CNRS/Université Lyon1, France, 3IRD, France, 4BiRC, Denmark, 5INRA, France
P-2221 Conservation of the Human Integrin-Type Beta-Propeller Domain in Bacteria
Bhanupratap Chouhan*1,2, Alexander Denesyuk1, Jyrki Heino3, Mark S. Johnson1, Konstantin Denessiouk2
1Department of Biosciences, Åbo Akademi University, Finland, 2Turku Center for Biotechnology (University of Turku and Åbo Akademi University), Finland, 3Department of Biochemistry and Food Chemistry, University of Turku, Finland
P-2114 Bayesian inference of the demographic history of Niger-Congo speaking populations
Isabel Alves*1,2, Lounès Chikhi2,3, Laurent Excoffier1,4
1CMPG, Institute of Ecology and Evolution, Switzerland, 2Population and Conservation Genetics Group, Instituto Gulbenkian de Ciência, Portugal, 3CNRS, Université Paul Sabatier, ENFA, France, 4Swiss Institute of Bioinformatics, Switzerland
P-2115 The porcine colonization of the Americas: A 60k SNP story
William Burgos-Paz*1, Carla Souza1,2, Hendrik-Jan Megens3, Samuel Paiva2, Martien Groenen3, Miguel Pérez-Enciso1,4, AmMap Consortium0
1Center for Research in Agricultural Genomics (CRAG) – Universitat Autònoma de Barcelona (UAB), Spain, 2Embrapa Recursos Genèticos e Biotecnologia – CENARGEN, Brazil, 3Animal Breeding and Genomics Centre, Wageningen University, The Netherlands, 4Institut de Recerca i Estudis Avançats de Catalunya, ICREA, Spain
P-2353 Evolution of the Rh family genes and the AVPR-OXTR family genes expressing in the kidney
Akinori Suzuki, Hironobu Ikeya, Mari Sugaya, Kaoru Yamashita, Kouhei Endo, Takashi Kitano*
Ibaraki University, Japan
P-2116 The worldwide spread of transposable element insertions associated with pesticide exposure and impact on linked polymorphism in Drosophila simulans.
Pierre Gerard*, Francois Wurmser, Romain Fougeyrollas, David Ogereau, Catherine Montchamp-Moreau
Lab Evolution Genome Speciation, CNRS-Universite Paris-Sud, France
P-2314 Transcriptome profiling studies in spruce trees reveal gene family evolution, high levels of diversity in gene expression and a novel insect resistance mechanism
Jukka-Pekka Verta1,2, Nathalie-Suzett Delvas2, Elie Raherison1,2, Isabelle Giguère1,2, Sébastien Caron1,2, Claude Bomal1,2, Éric Bauce2, Christian Landry1, John MacKay*1,2
1Institute of integrative and systems biology, Laval University, Canada, 2Center for forest research, Laval University, Canada
P-2117 Transformations of the site frequency spectrum and application to human populations
Alexander Klassmann, Thomas Wiehe*
Universitaet zu Koeln, Germany
P-2222 Evolution of gene structure in conifers.
Juliana Sena*1, Isabelle Giguère1, Brian Boyle1, Kermit Ritland2, Jean Bousquet1, John Mackay1
1Institute for Systems and Integrative Biology and Center for Forest Research, Université Laval, Canada, 2Department of Forest Sciences, University of British Columbia, Canada
P-2172 Asymmetric evolution of Bmp16 and its sister genes Bmp2 and Bmp4
Nathalie Feiner*1, Gerrit Begemann1, Axel Meyer1, Shigehiro Kuraku1,2
1University of Konstanz, Germany, 2Center for Developmental Biology RIKEN, Japan
P-2223 Genomic structure and evolution of multigene families: "Flowers" on the human genome
Hie Lim Kim*1,4, Mineyo Iwase1, Satoko Kaneko2, Yukako Katsura1, Takeshi Igawa3, Tasuku Nishioka1, Naoyuki Takahata1, Yoko Satta1
1The Graduate University for Advanced Studies (Sokendai), Japan, 2Kyoto University, Japan, 3Hiroshima University, Japan, 4Pennsylvania State University, USA
P-2185 Identifying  long range cis-regulation in the human genome using evolutionary co-segregation
Magali Naville*, Alexandra Louis, Hugues Roest Crollius
ENS, France
P-2118 Population genomics of threespine stickleback after 30-year evolution experiment
Nadezhda Terekhanova*1, Nicolai Mugue2, Georgii Bazykin1,4, Alexey Kondrashov1,3
1Lomonosov Moscow State University, Faculty of Bioengineering and Bioinformatics, Russia, 2Institute of Developmental Biology RAS / VNIRO, Russia, 3Life Sciences Institute, USA, 4A. A. Kharkevich Institute for Information Transmission Problems, Russia
P-2119 A genetic study of skin pigmentation variation in India
Mircea Iliescu*1, Chandana Basu Mallick2,3, Niraj Rai4, Anshuman Mishra4, Gyaneshwer Chaubey2, Rakesh Tamang4, Märt Möls3, Rie Goto1, Georgi Hudjashov2,3, Srilakshmi Raj1, Ramasamy Pitchappan5, CG Nicholas Mascie-Taylor1, Lalji Singh4,6, Marta Mirazon-Lahr7, Mait Metspalu2,3, Kumarasamy Thangaraj4, Toomas Kivisild1,3
1Division of Biological Anthropology, University of Cambridge, UK, 2Evolutionary Biology Group, Estonian Biocentre, Estonia, 3Institute of Molecular and Cell Biology, University of Tartu, Estonia, 4Centre for Cellular and Molecular Biology, India, 5Chettinad Academy of Research and Education, Chettinad Health City, India, 6Banaras Hindu University, India, 7Leverhulme Centre for Human Evolutionary Studies, Division of Biological Anthropology, University of Cambridge, UK
P-2259 Photoactivation of zebrafish rhodopsin: insights into the molecular evolution of retinal release.
James Morrow*, Belinda Chang
University of Toronto, Canada
P-2354 Investigating the expansion of gene families in otherwise reduced microsporidian genomes
Sirintra Nakjang1, Tom Williams1, Andrew Watson*1, Peter Foster2, Eva Heinz1, Robert Hirt1, Martin Embley1
1Newcastle University, UK, 2Natural History Museum, UK
P-2315 Characterizing the X-autosome difference in regulation of testes-specific genes in Drosophila melanogaster
Emily Landeen*, Colin Meiklejohn, Daven Presgraves
University of Rochester, USA
P-2158 A multiplex platform for continuous culture and experimental evolution in yeast
Aaron Miller*, Mei Huang, Annie Young, Bryony Lynch, Maitreya Dunham
University of Washington, USA
P-2377 Y-by-background effects on global gene expression in Drosophila melanogaster
Pan-Pan Jiang*, Bernardo Lemos, Lene Martinsen, Daniel Hartl
Harvard University, USA
P-2120 Stepwise colonization of the Andes by Ruddy Ducks dispersing from North America accompanied by the evolution of novel beta-globin variants
Violeta Munoz-Fuentes*1,4, Maria Cortázar Chinarro4, Maria Lozano3, Kevin McCracken2
1Estacion Biologica de Donana-CSIC, Spain, 2University of Alaska Fairbanks, USA, 3Universidad de Los Andes, Colombia, 4Uppsala University, Sweden
Barbara Ottolini*, Edward J. Hollox
University of Leicester, UK
P-2186 Using Transcription Factor Binding Site Motifs to Predict Enhancer Function for Noncoding Sequences
Dennis Kostka*1,4, Katherine S. Pollard2,3
1Department of Developmental Biology, University of Pittsburgh, USA, 2Gladstone Institute of Cardiovascular Disease, University of California San Francisco, USA, 3Division of Biostatistics and Institute of Human Genetics, University of California San Francisco, USA, 4Department of Computational and Systems Biology, University of Pittsburgh, USA
P-2316 Characterization of the olfactory transcriptome in the European eel Anguilla anguilla
Allison Churcher*1, Weiming Li2, Scot Libants2, Alessandro Coppe3, Lorenzo Zane3, Adelino Canário1, Mar Huertas1
1Centre of Marine Science, University of Algarve, Portugal, 2Michigan State University, USA, 3University of Padova, Italy
P-2159 Genomewide association study for melanoma susceptibility
Susanne Horn
German Cancer Research Center, Germany
P-2160 Adaptive evolution of Mediterranean pines
Delphine Grivet1, Zaida Lorenzo*1, José Climent1, Mario Zabal-Aguirre1, Sara Torre4, David B. Neale2,3, Giovanni G. Vendramin4, Santiago C. González Martínez1
1INIA-CIFOR, Spain, 2Department of Plant Sciences,University of California, Davis, USA, 3Center for Population Biology, University of California, Davis, USA, 4Plant Genetics Institute, Division of Florence, National Research Council, Sesto Fiorentino, Italy
P-2121 Genetic Differentiation and Local Adaptation of an Ecologically Dominant Prairie Grass Andropogon gerardii (Big Bluestem) Occurring Along a Natural Precipitation Gradient in Midwest US Grasslands
Loretta Johnson*1, Miranda Gray1, Paul St Amand2, Eduard Akhunov1, Karen Garrett1, Mary Knapp1, Ted Morgan1, Bai Guihua2, Sara Baer4, Brian Maricle3, Hannah Tetreault1
1Kansas State University, USA, 2United States Department of Agriculture Agricultural Research Service, Hard Winter Wheat Genetics Research Unit,, USA, 3Fort Hays State University, USA, 4Southern Illinois University, USA
P-2365 PHYRN: A Robust Method for Phylogenetic Analysis of Highly Divergent Sequences
Gaurav Bhardwaj*1, Sree Chintapalli1, Yoojin Hong0,2, Zhenhai Zhang0,2, Edward Holmes0,2, Damian van Rossum0,2, Randen Patterson1
1University of California, Davis, USA, 2Pennsylvania State University, USA
P-2317 Muller’s ratchet and hybrid origins of apomixis:  high quality SNP discovery in the Ranunculus auricomus complex
Marco Pellino*, Diego Hojsgard, Thomas Schmutzer, Elvira Hörandl, Timothy Sharbel
IPK institute, Germany
P-2383 The genetic impact of infectious disease on indigenous southern African populations
Katharine Owers
Uppsala University, Sweden
P-2384 Pairwise Evolutionary Distance Estimation Under Alignment Uncertainty
Ge Tan
Department of Computer Science ETH Zuerich, Switzerland
P-2385 Birth, death, and replacement of karyopherins in Drosophila
Emily Hsieh*, Nitin Phadnis, Harmit S. Malik
Fred Hutchinson Cancer Research Center, Seattle, USA
P-2386 Emergence of multicellular novelty
Chelsea Du Fresne
University of Minnesota- Twin Cities, USA
P-2387 Genetic variation of Symbiodinium spp. of the coral host Agaricia lamarcki between shallow and mesophotic habitats
Ramon Rivera Vicens
University of Puerto Rico, Puerto Rico
P-2388 Prevalence and Genetic Diversity of Microsporidia intracellular parasites across fire ant species in South America
Gebreyes Kassu
University of Florida, USA
P-2382 The asymptotic null distribution of certain likelihood ratio test statistics for detecting natural selection in codon sequences
Jean Kai Ling Lim
National University of Singapore, Singapore
P-2381 A Search For Fusions Of Unrelated Genes In The Yeast Genome
Leanne M. Murphy*, Leanne S. Haggerty
National University of Ireland Maynooth, Ireland