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S17 - Molecular, Genomic, and Phenotypic Evolvability
Monday 25th June 2012, 16:30-18:00
Liffey Hall 2
O-177 Evolution of evolvability of the var gene family in malaria
Adam F. Sander1, Thomas Lavstsen1, Thomas S. Rask2, Michael Lisby4, Thomas P. Gilbert3, Ali Salanti1, Sarah L. Fordyce3, Jakob S. Jespersen1, Eske Willerslev3, Richard Carter5, Thor G. Theander1, Anders Gorm Pedersen*2, David E. Arnot1,5
1Centre for Medical Parasitology, University of Copenhagen, Denmark, 2Center for Biological Sequence Analysis, Technical University of Denmark, Denmark, 3Centre for GeoGenetics, University of Copenhagen, Denmark, 4Department of Biology, University of Copenhagen, Denmark, 5Institute of Infection & Immunology Research, University of Edinburgh, UK
O-178 “Proto-genes” and de novo gene birth
Anne-Ruxandra Carvunis*1,2, Thomas Rolland1, Ilan Wapinski3, Muhammed Yildirim1, Nicolas Simonis1, Benoit Charloteaux1, Cesar Hidalgo4, Michael Calderwood1, Balaji Santhanam1, Gloria Brar5, Jonathan Weissman5, Aviv Regev6, Nicolas Thierry-Mieg2, Michael Cusick1, Marc Vidal1
1Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, and Department of Genetics, Harvard Medical School, USA, 2UJF-Grenoble 1 / CNRS / TIMC-IMAG UMR 5525, Computational and Mathematical Biology Group, France, 3Department of Systems Biology, Harvard Medical School, USA, 4The MIT Media Lab, Massachusetts Institute of Technology, USA, 5Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, USA, 6Broad Institute of MIT and Harvard, USA
O-179 The microbial lag phase is an evolvable trait that underlies specialist and generalist growth strategies.
Aaron New*1,2, Sander Govers1,2, Bram Cerulus1,2, Joao Xavier3, Kevin Verstrepen1,2
1VIB Laboratory of Systems Biology, Belgium, 2CMPG Laboratory of Genetics and Genomics, Belgium, 3Program in Computational Biology, Memorial Sloan Kettering Cancer Center, USA
O-180 Quantitative analysis of genetic and environmental factors determining variation in cell growth
Naomi Ziv*, Mark Siegal, David Gresham
New York University, USA
O-181 Molecular basis of increased evolvability as a result of multicellularity evolution
Maria Rebolleda-Gomez*1, Johnathon Fankhauser3, William C. Ratcliff1, Michael Travisano1,2
1Ecology, Evolution and Behavior deppartment, University of Minnesota, USA, 2Biotechology Institute, University of Minnesota, USA, 3Plant Sciences, University of Minnesota, USA
O-182 Experimental evolution of a viral protease
Thomas Shafee*, Pietro Gatti-Lafranconi, Florian Hollfelder
University of Cambridge, UK